Changes

==Signalment==

==Signalment==

*Often affects older animals but kittens of 16 weeks old and puppies of 20 weeks old have been reported.  

*Often affects older animals but kittens of 16 weeks old and puppies of 20 weeks old have been reported.  

==Description==

==Description==

'''Lymphocytic - plasmacytic enteritis (LPE)''' is the most common form of [[Inflammatory Bowel Disease|Inflammatory Bowel Disease]] (IBD).  As its name suggests, the predominant cell type in the intestinal mucosa is [[Lymphocytes - Introduction|'''lymphocytes''']] and '''plasma cells'''.  Enteric parasites, bacteria in dogs and [[Toxoplasma|''Toxoplasma'']] in cats have been reported to associated with LPE.  This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as [[Pancreatitis - Dog and Cat|pancreatitis]], [[Cholangitis|cholangitis]] and [[Hepatic Lipidosis|hepatic lipidosis]].  LPE is believed to be caused by an abnormal [[Regional Lymphoid Tissue - Anatomy & Physiology|mucosal associated lymphoid tissue (MALT)]] response to luminal bacterial, dietary or self-antigens.   

'''Lymphocytic - plasmacytic enteritis (LPE)''' is the most common form of [[Inflammatory Bowel Disease|Inflammatory Bowel Disease]] (IBD).  As its name suggests, the predominant cell type in the intestinal mucosa is [[Lymphocytes - Introduction|'''lymphocytes''']] and '''plasma cells'''.  Enteric parasites, bacteria in dogs and [[Toxoplasma gondii|''Toxoplasma'']] in cats have been reported to associated with LPE.  This disorder in cats have also been shown to associate with concurrent disease of the pancreas and liver such as [[Pancreatitis|pancreatitis]], [[Cholangitis|cholangitis]] and [[Hepatic Lipidosis|hepatic lipidosis]].  LPE is believed to be caused by an abnormal [[Regional Lymphoid Tissue - Anatomy & Physiology|mucosal associated lymphoid tissue (MALT)]] response to luminal bacterial, dietary or self-antigens.   

The [[Small Intestine - Anatomy & Physiology|small intestines]] are affected to a variable degree of severity.  It has also been known to affect other parts of the gastrointestinal tract such as the [[:Category:Stomach and Abomasum - Pathology|stomach]] and the [[Colon - Anatomy & Physiology|colon]].  In severely affected animals, this will result in a protein-losing enteropathy (PLE).

The [[Small Intestine Overview - Anatomy & Physiology|small intestines]] are affected to a variable degree of severity.  It has also been known to affect other parts of the gastrointestinal tract such as the [[:Category:Stomach and Abomasum - Pathology|stomach]] and the [[Colon - Anatomy & Physiology|colon]].  In severely affected animals, this will result in a protein-losing enteropathy (PLE).

==Diagnosis==

==Diagnosis==

*** Changes in the relative and absolute numbers of plasma cells and lymphocytes have been  associated with IBD in humans.

*** Changes in the relative and absolute numbers of plasma cells and lymphocytes have been  associated with IBD in humans.

[[Category:Intestine_-_Inflammatory_Pathology_by_Type]][[Category:To_Do_-_Stuartd]]

 

[[Category:Intestine_-_Inflammatory_Pathology_by_Type]][[Category:To_Do_-_Alimentary]][[Category:To Do - Medium]]