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Small Animal Dermatology Q&A 16 (view source)
Revision as of 11:34, 6 June 2011
, 11:34, 6 June 2011Created page with "{{Template:Manson Moriello}} centre|500px<br> <br /> '''A 2-year-old blue doberman pinscher dog was referred for the problem of an..."
{{Template:Manson Moriello}}
[[Image:Small Animal Dermatology Q&A 16.jpg|centre|500px]]<br>
<br />
'''A 2-year-old blue doberman pinscher dog was referred for the problem of an ‘endocrine alopecia’ of unknown etiology. Previous diagnostic tests were normal or negative and included: skin scrapings, dermatophyte culture, complete blood count, urinalysis, serum chemistry panel, thyroid hormone evaluation, low-dose dexamethasone suppression test, and surgical neutering. Dermatological examination reveals a thin hair coat, nodular-like hair follicles, comedones, bacterial pyoderma, and scaling. All of the other littermates are similarly affected.'''
<br />
<FlashCard questions="3">
|q1=What is the most likely diagnosis, and what is the cause?
|a1=
Color dilution alopecia (previously called color mutant alopecia). This is a genetic disorder of the hair coat commonly associated with a blue or fawn coat color. The cause is unknown, but it is believed to be due, in part, to a defect in the coat color genes at the D locus.<br><br>
Affected dogs are born with normal hair coats and, as they mature, they develop
*hair loss on the dorsum,
*recurrent bacterial infections,
*generalized thinning of the hair coat,
*secondary seborrhea, and
*cystic or dilated hair follicles. <br>
As hairs regrow, they grow more slowly and are often deformed. This disorder has been seen in cats with blue or cream colored coats.
|l1=
|q2=How is this disorder treated?
|a2=
There is no effective treatment for this disorder. In the early stages of the disorder, hair loss is caused by hair shaft fracture. <br><br>
As a result, excessive grooming and harsh shampoos should be avoided. It is important to control the recurrent bacterial pyodermas associated with this disorder. <br><br>
Affected dogs will continue to lose hair, and many are alopecic by 2–3 years of age.
|l2=
|q3=What are the most common histological findings?
|a3=
Common histological findings show melanin clumping in the epidermal and follicular basal cells, macromelanosomes in the hair shafts or hair bulbs, and follicular dysplasia. <br><br>
The melanin clumping and macromelanosomes are key findings for diagnosis of this disease.
|l3=
</FlashCard>
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[[Category:Small Animal Dermatology Q&A]]
[[Image:Small Animal Dermatology Q&A 16.jpg|centre|500px]]<br>
<br />
'''A 2-year-old blue doberman pinscher dog was referred for the problem of an ‘endocrine alopecia’ of unknown etiology. Previous diagnostic tests were normal or negative and included: skin scrapings, dermatophyte culture, complete blood count, urinalysis, serum chemistry panel, thyroid hormone evaluation, low-dose dexamethasone suppression test, and surgical neutering. Dermatological examination reveals a thin hair coat, nodular-like hair follicles, comedones, bacterial pyoderma, and scaling. All of the other littermates are similarly affected.'''
<br />
<FlashCard questions="3">
|q1=What is the most likely diagnosis, and what is the cause?
|a1=
Color dilution alopecia (previously called color mutant alopecia). This is a genetic disorder of the hair coat commonly associated with a blue or fawn coat color. The cause is unknown, but it is believed to be due, in part, to a defect in the coat color genes at the D locus.<br><br>
Affected dogs are born with normal hair coats and, as they mature, they develop
*hair loss on the dorsum,
*recurrent bacterial infections,
*generalized thinning of the hair coat,
*secondary seborrhea, and
*cystic or dilated hair follicles. <br>
As hairs regrow, they grow more slowly and are often deformed. This disorder has been seen in cats with blue or cream colored coats.
|l1=
|q2=How is this disorder treated?
|a2=
There is no effective treatment for this disorder. In the early stages of the disorder, hair loss is caused by hair shaft fracture. <br><br>
As a result, excessive grooming and harsh shampoos should be avoided. It is important to control the recurrent bacterial pyodermas associated with this disorder. <br><br>
Affected dogs will continue to lose hair, and many are alopecic by 2–3 years of age.
|l2=
|q3=What are the most common histological findings?
|a3=
Common histological findings show melanin clumping in the epidermal and follicular basal cells, macromelanosomes in the hair shafts or hair bulbs, and follicular dysplasia. <br><br>
The melanin clumping and macromelanosomes are key findings for diagnosis of this disease.
|l3=
</FlashCard>
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[[Category:Small Animal Dermatology Q&A]]