Difference between revisions of "Chicken Anaemia Virus Disease Flashcards"
Jump to navigation
Jump to search
| Line 57: | Line 57: | ||
*Chicks older than 14 days old do not show any clinical signs if infected via horizontal transmission. | *Chicks older than 14 days old do not show any clinical signs if infected via horizontal transmission. | ||
|l8=Chicken Anaemia Virus Disease#Clinical Signs | |l8=Chicken Anaemia Virus Disease#Clinical Signs | ||
| − | |q9= | + | |q9=How is ''Chicken anaemia virus disease transmitted? |
|a9= | |a9= | ||
| − | * | + | *Horizontally through fomites and faecal-oral as the virus is excreted by a small number of vertically infected hatch mates. This occurs in older chickens that lack maternal derived antibodies. |
| − | + | *Vertically as chicks hatch from infected layers of naive flocks over a period of 3 to 6 weeks. After this period the breeder layers develop sufficient CAV antibodies to stop the transmission of the virus to the egg. Clinical signs are seen in 10-14 day old chicks. | |
| − | |l9=Chicken Anaemia Virus Disease# | + | |l9=Chicken Anaemia Virus Disease#Epidemiology |
| − | |q10= | + | |q10=How many serotypes of CAV are there? |
| − | |a10= | + | |a10=One |
| − | * | + | |l10=Chicken Anaemia Virus Disease#Epidemiology |
| − | + | |q11=How can CAV isolates be distinguished?|a11=Restriction endonuclease analysis of amplified DNA. | |
| − | | | + | |l11=Chicken Anaemia Virus Disease#Epidemiology |
| + | |q12=What is the mortality rates within the flock? | ||
| + | |a12= | ||
| + | *5 to 10% (but can be as high as 60%). | ||
| + | *Mortality peaks during the third week of life | ||
| + | |l12=Chicken Anaemia Virus Disease#Epidemiology | ||
| + | |q13=What is the distribution of CAV? | ||
| + | |a13=Worldwide - distribution including commercial poultry and specific pathogen free (SPF) flocks. | ||
| + | |l13=Chicken Anaemia Virus Disease#Distribution | ||
| + | |q14=How do you diagnose ''Chicken anaemia virus disease''? | ||
| + | |a14= | ||
| + | *Clinical signs | ||
| + | *Decreases in haematocrit from normal ranges (32-37.5%) to below 27% | ||
| + | *Increases in the amount of immature blood cells | ||
| + | *Virus isolation (confirms diagnosis) - but growth of CAV in cell cultures can be difficult. | ||
| + | Levels of infection can be estimated by the detection of raising antibody titres. | ||
| + | |||
| + | Many diagnostic tests have been develop: | ||
| + | *Immunoperoxidase staining | ||
| + | *ELISA | ||
| + | *PCR | ||
| + | *Dot blot hybridisation | ||
| + | *Indirect immunofluorescence | ||
| + | |l14=Chicken Anaemia Virus Disease#Diagnosis | ||
| + | Post mortem findings include: | ||
| + | *severe atrophy of the lymphoid organs. The thymus, bursa of Fabricius, and to a lesser extent the spleen are all affected by a depletion of lymphocytes and sequential hyperplasia of reticular cells. Common finding include haemorrhages throughout the skeletal muscle and subcutaneous tissue and pale watery bone marrow. Severe aplasia of the bone marrow occurs and haematopoietic cells are replaced with adipose tissue, giving the bone marrow its watery texture and characteristic change in colour from red to yellow. | ||
| + | |l14=Chicken Anaemia Virus Disease#Epidemiology | ||
| + | |q15=What can be found on postmortem? | ||
| + | |a15= | ||
| + | *Severe atrophy of the lymphoid organs (thymus, bursa of Fabricius, and to a lesser extent the spleen). All become depleted of lymphocytes and reticular cells become hyperplastic. | ||
| + | *Haemorrhages throughout the skeletal muscle and subcutaneous tissue | ||
| + | *Pale watery yellow bone marrow - due to severe aplasia of the BM and the haematopoietic cells being replaced with adipose tissue | ||
| + | |l15=Chicken Anaemia Virus Disease#Diagnosis | ||
| − | |||
</FlashCard> | </FlashCard> | ||
Revision as of 11:20, 29 June 2011
| Question | Answer | Article | |
| What is Chicken Anaemia Virus Disease also commonly known as? |
|
Link to Article | |
| Which virus causes Chicken Anaemia Virus Disease and what are it's properties? | Chicken anaemia virus (CAV):
|
Link to Article | |
| What family does the Chicken anaemia virus (CAV) belong to? | Circoviridae
|
Link to Article | |
| What chemicals destroy the virus? |
|
Link to Article | |
| How many proteins does CAV produce? | Three:
Vaccines need to contain both VP1 and VP2 to be antigenic. Due to VP3 apoptotic properties it has the potential to be an anti-cancer agent. |
Link to Article | |
| Is Chicken anaemia virus disease considered to be a zoonosis? | No
|
Link to Article | |
| What species of birds does the CAV infect? |
|
Link to Article | |
| What are the clinical signs of Chicken Anaemia Virus Disease? | Clinical signs include:
Neurological signs include:
|
Link to Article | |
| How is Chicken anaemia virus disease transmitted? |
|
Link to Article | |
| How many serotypes of CAV are there? | One
|
Link to Article | |
| How can CAV isolates be distinguished? | Restriction endonuclease analysis of amplified DNA.
|
Link to Article | |
| What is the mortality rates within the flock? |
|
Link to Article | |
| What is the distribution of CAV? | Worldwide - distribution including commercial poultry and specific pathogen free (SPF) flocks.
|
Link to Article | |
| How do you diagnose Chicken anaemia virus disease? |
Levels of infection can be estimated by the detection of raising antibody titres. Many diagnostic tests have been develop:
|
Link to Article | |