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{{Template:Manson}}
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{{Template:Manson Scott Sheep}}
    
[[Image:Sheep Medicine 4.jpg|centre|500px]]
 
[[Image:Sheep Medicine 4.jpg|centre|500px]]
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The poor growth rates of this group of lambs could be the result of poor grazing, overstocking, PGE, and trace element deficiency acting alone or in various combinations. <br>
 
The poor growth rates of this group of lambs could be the result of poor grazing, overstocking, PGE, and trace element deficiency acting alone or in various combinations. <br>
 
The neurological signs are consistent with a diffuse cortical lesion – most likely a hepatic encephalopathy.
 
The neurological signs are consistent with a diffuse cortical lesion – most likely a hepatic encephalopathy.
|l1=
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|l1= Cobalt Deficiency - Sheep
 
|q2=How would you investigate this problem?  
 
|q2=How would you investigate this problem?  
 
|a2=
 
|a2=
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*Liver enzyme concentrations (AST, GLDH, and GGT) are raised four- to six-fold in the four lambs sampled.  
 
*Liver enzyme concentrations (AST, GLDH, and GGT) are raised four- to six-fold in the four lambs sampled.  
 
*Serum vitamin B 12 concentration from six lambs reveal very low levels (mean <88.6 pmol/L, <120 pg/mL).  
 
*Serum vitamin B 12 concentration from six lambs reveal very low levels (mean <88.6 pmol/L, <120 pg/mL).  
|l2=
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|l2= Cobalt Deficiency - Sheep#Diagnosis
 
|q3=What treatments would you administer?
 
|q3=What treatments would you administer?
 
|a3=
 
|a3=
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Two of 12 lambs failed to respond to vitamin B 12 and supportive therapy and were euthanased for welfare reasons. <br>
 
Two of 12 lambs failed to respond to vitamin B 12 and supportive therapy and were euthanased for welfare reasons. <br>
 
Necropsy revealed a pale and friable liver.  
 
Necropsy revealed a pale and friable liver.  
|l3=
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|l3= Cobalt Deficiency - Sheep#Treatment
 
|q4=How would you prevent a similar problem next year?  
 
|q4=How would you prevent a similar problem next year?  
 
|a4=
 
|a4=
 
The low unit cost of cobalt sulphate allows routine inclusion in anthelmintic drenches (commercial ‘SC’ preparations, or at inclusion rates of 15–30 g per 10 L of 2.25% benzimidazole or 1.5% levamisole drench).  
 
The low unit cost of cobalt sulphate allows routine inclusion in anthelmintic drenches (commercial ‘SC’ preparations, or at inclusion rates of 15–30 g per 10 L of 2.25% benzimidazole or 1.5% levamisole drench).  
|l4=
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|l4= Cobalt Deficiency - Sheep#Control
 
</FlashCard>
 
</FlashCard>
  
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