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Rabbit Medicine and Surgery Q&A 05 (view source)
Revision as of 17:41, 10 August 2011
, 17:41, 10 August 2011Created page with "{{Template:Manson Keeble Meredith}} centre|500px <br /> '''A rapid Romanovsky-type (Rapid-Diff) stained blood smear from a seven-year-old neut..."
{{Template:Manson Keeble Meredith}}
[[Image:Rabbit Medicine 05.jpg|centre|500px]]
<br />
'''A rapid Romanovsky-type (Rapid-Diff) stained blood smear from a seven-year-old neutered female Dwarf Lop house rabbit, with a severe regenerative anaemia, is shown. The PCV was 0.14 l/l (14%); Hb was 27 g/l (2.7 g/dl). The rabbit was presented with gradually increasing lethargy and decreased appetite of several weeks’ duration.'''
<br />
<FlashCard questions="4">
|q1=Characterize the anaemia from the red cell morphology.
|a1=
Polychromatic, anisocytotic anaemia.
|l1=
|q2=What stain may be used to differentiate reticulocytes more accurately?
|a2=
New methylene blue.
|l2=
|q3=What is the most likely cause of this anaemia, and give a differential diagnosis.
|a3=Plumbism (lead toxicosis). In this case it occurred because the rabbit gnawed at painted skirting boards in the house. Although currently manufactured house paints do not contain lead salt pigments, in many cases old paint layers are not removed but simply painted over with new paint.<br><br>
The serum lead level in this case was 12.0 μmol/l. <br><br>
Other less frequent differentials for a regenerative anaemia include
*blood loss due to trauma,
*intestinal or internal haemorrhage,
*intravascular haemolysis or
*severe flea infestation. <br>
Chronic disease and neoplasia such as uterine adenocarcinoma are more likely to manifest as a non-regenerative anaemia.
|l3=
|q4=What other haematological and biochemistry abnormalities may occur with this condition?
|a4=Lead toxicosis may also manifest in cytoplasmic basophilic stippling, and the regenerative response may lead to the presence of nucleated erythrocytes and metarubricytes on blood smears. <br><br>
Resultant hepatic damage may result in elevations in ALP, ALT and bilirubin levels,
|l4=
</FlashCard>
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[[Category:Rabbit Medicine and Surgery Q&A]]
[[Image:Rabbit Medicine 05.jpg|centre|500px]]
<br />
'''A rapid Romanovsky-type (Rapid-Diff) stained blood smear from a seven-year-old neutered female Dwarf Lop house rabbit, with a severe regenerative anaemia, is shown. The PCV was 0.14 l/l (14%); Hb was 27 g/l (2.7 g/dl). The rabbit was presented with gradually increasing lethargy and decreased appetite of several weeks’ duration.'''
<br />
<FlashCard questions="4">
|q1=Characterize the anaemia from the red cell morphology.
|a1=
Polychromatic, anisocytotic anaemia.
|l1=
|q2=What stain may be used to differentiate reticulocytes more accurately?
|a2=
New methylene blue.
|l2=
|q3=What is the most likely cause of this anaemia, and give a differential diagnosis.
|a3=Plumbism (lead toxicosis). In this case it occurred because the rabbit gnawed at painted skirting boards in the house. Although currently manufactured house paints do not contain lead salt pigments, in many cases old paint layers are not removed but simply painted over with new paint.<br><br>
The serum lead level in this case was 12.0 μmol/l. <br><br>
Other less frequent differentials for a regenerative anaemia include
*blood loss due to trauma,
*intestinal or internal haemorrhage,
*intravascular haemolysis or
*severe flea infestation. <br>
Chronic disease and neoplasia such as uterine adenocarcinoma are more likely to manifest as a non-regenerative anaemia.
|l3=
|q4=What other haematological and biochemistry abnormalities may occur with this condition?
|a4=Lead toxicosis may also manifest in cytoplasmic basophilic stippling, and the regenerative response may lead to the presence of nucleated erythrocytes and metarubricytes on blood smears. <br><br>
Resultant hepatic damage may result in elevations in ALP, ALT and bilirubin levels,
|l4=
</FlashCard>
{{#tag:imagemap|Image:Next Question.png{{!}}center{{!}}200px
rect 0 0 860 850 [[Rabbit Medicine and Surgery Q&A 06|Rabbit Medicine and Surgery Q&A 06]]
desc none}}
[[Category:Rabbit Medicine and Surgery Q&A]]