Difference between revisions of "Actinobacillus species"
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− | # | + | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> |
+ | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | ||
+ | |||
+ | * Cause [[Peritoneal cavity - inflammatory#In horses|peritonitis in horses]] | ||
+ | * ''A. pleuropneumoniae'' causes [[Bacterial infections#Actinobacillus pleuropneumoniae|pneumonia]] in pigs | ||
+ | * Cause [[General Pathology - Chronic Inflammation#Granulomatous Inflammation|granulomatous inflammation]]. | ||
+ | ** E.g. ''Actinobacillus lignieresii'' causes wooden tongue in cattle -> [[Muscles - inflammatory#Wooden tongue|myositis]] | ||
+ | *''A. equuli'' in [[Joints - inflammatory#In Horses|arthritis of horses]] | ||
+ | |||
+ | ===Overview=== | ||
+ | |||
+ | |||
+ | ===''Actinobacillus'' characteristics=== | ||
+ | |||
+ | *Small Gram negative coccobacilli | ||
+ | *Oxidase negative | ||
+ | *Do not grow on MacConkey | ||
+ | |||
+ | |||
+ | ===''Actinobacillus lignieresii''=== | ||
+ | |||
+ | *Commensal in the mouth of sheep and cattle | ||
+ | *Penetrates damaged mucosa to cause a granuloma, a condition known as Actinobacillosis | ||
+ | *Enodogenous, sporadic and chronic infection | ||
+ | *Lesions in the tongue, cheek, lips and sometimes in the lower gut and lungs from aspiration | ||
+ | *Often spreads from the site of infection to lymphatics | ||
+ | *Formation of fibrous tissue in the lesions lead to hardening of the tissue, hence the condition is known as 'wooden tongue' in cattle | ||
+ | *In sheep abscesses with thick walls are produced | ||
+ | *Feeding is impaired, causing loss of condition | ||
+ | *Recovery with antibiotics | ||
+ | |||
+ | |||
+ | ===''Actinobacillus equuli''=== | ||
+ | |||
+ | *Commensal of the equine intestinal mucosa | ||
+ | *Infection at birth causes severe enteritis and septicaemia within 24 hours, known as sleepy foal disease | ||
+ | *In foals that survive neonatal infection the condition progresses to cause joint infections and purulent nephritis | ||
+ | *RTX group cytotoxin present | ||
+ | |||
+ | |||
+ | ===''Actinobacillus suis''=== | ||
+ | |||
+ | *Fatal septicaemia in pigs 1-8 weeks old | ||
+ | *Causes abscesses in joints and lungs of older pigs | ||
+ | *Carried in the nasopharynx of pigs and nose of horses | ||
+ | *Carriage may confer immunity to the more severe pleuropneumonia | ||
+ | |||
+ | |||
+ | ===''Actinobacillus pleuropneumoniae''=== | ||
+ | |||
+ | *Contagious porcine pleuropneumonia | ||
+ | *Endemic in UK | ||
+ | *Most strains are NAD-dependent (grow on Heated Blood agar) | ||
+ | *Positive CAMP reaction | ||
+ | *12 serotypes causing the same disease | ||
+ | *Different serotypes in different regions, with serotypes 3,6 and 8 the most common in the UK | ||
+ | * |
Revision as of 17:44, 17 December 2007
- Cause peritonitis in horses
- A. pleuropneumoniae causes pneumonia in pigs
- Cause granulomatous inflammation.
- E.g. Actinobacillus lignieresii causes wooden tongue in cattle -> myositis
- A. equuli in arthritis of horses
Overview
Actinobacillus characteristics
- Small Gram negative coccobacilli
- Oxidase negative
- Do not grow on MacConkey
Actinobacillus lignieresii
- Commensal in the mouth of sheep and cattle
- Penetrates damaged mucosa to cause a granuloma, a condition known as Actinobacillosis
- Enodogenous, sporadic and chronic infection
- Lesions in the tongue, cheek, lips and sometimes in the lower gut and lungs from aspiration
- Often spreads from the site of infection to lymphatics
- Formation of fibrous tissue in the lesions lead to hardening of the tissue, hence the condition is known as 'wooden tongue' in cattle
- In sheep abscesses with thick walls are produced
- Feeding is impaired, causing loss of condition
- Recovery with antibiotics
Actinobacillus equuli
- Commensal of the equine intestinal mucosa
- Infection at birth causes severe enteritis and septicaemia within 24 hours, known as sleepy foal disease
- In foals that survive neonatal infection the condition progresses to cause joint infections and purulent nephritis
- RTX group cytotoxin present
Actinobacillus suis
- Fatal septicaemia in pigs 1-8 weeks old
- Causes abscesses in joints and lungs of older pigs
- Carried in the nasopharynx of pigs and nose of horses
- Carriage may confer immunity to the more severe pleuropneumonia
Actinobacillus pleuropneumoniae
- Contagious porcine pleuropneumonia
- Endemic in UK
- Most strains are NAD-dependent (grow on Heated Blood agar)
- Positive CAMP reaction
- 12 serotypes causing the same disease
- Different serotypes in different regions, with serotypes 3,6 and 8 the most common in the UK