Changes

==Introduction==

==Introduction==

At the physis, if the blood supply is deficient, there is a '''failure of endochondral ossification''' and the cartilage matrix does not become mineralised or replaced by bone. This is regarded as a form of [[Osteochondrosis|osteochondrosis]].

At the physis, if the blood supply is deficient, there is a '''failure of [[Bone & Cartilage Development - Anatomy & Physiology#2. Endochondral Ossification|

endochondral ossification]]''' and the cartilage matrix does not become mineralised or replaced by bone. This is regarded as a form of [[Osteochondrosis|osteochondrosis]].

In the distal ulna, the metaphysis is flared and is of a large diameter. This may influence the blood supply to the cartilage that is normally found on the metaphyseal side of the physis and may cause a '''large core of cartilage''' to accumulate within the metaphysis.

In the distal ulna, the metaphysis is flared and is of a large diameter. This may influence the blood supply to the cartilage that is normally found on the metaphyseal side of the physis and may cause a '''large core of cartilage''' to accumulate within the metaphysis.

Many affected dogs are '''asymptomatic''', and RCC may be an incidental finding.

Many affected dogs are '''asymptomatic''', and RCC may be an incidental finding.

In some dogs, there may be '''limb deformities''' such as valgus deviation and external rotation of the carpus in the forelimb. Cranial bowing of the radius may also be present.

In some dogs, there may be [[Angular Limb Deformity|'''limb deformities''']] such as valgus deviation and external rotation of the carpus in the forelimb. Cranial bowing of the radius may also be present.

There may be '''pain and lameness''' if the decrease in growth rate of the ulna is severe.

There may be '''pain and lameness''' if the decrease in growth rate of the ulna is severe.

==Prognosis==

==Prognosis==

Any deformity, if present, will probably be a permenant feature.  

Any deformity, if present, will probably be a permanent feature.  

If deformity has developped rapidly in a giant breed, the prognosis for correction is '''poor''' and the limb will most likely not touch the ground when the dog reaches maturity.

If deformity has developed rapidly in a giant breed, the prognosis for correction is '''poor''' and the limb will most likely not touch the ground when the dog reaches maturity.

{{Learning

{{Learning

Morgan, J. (2000) '''Hereditary bone and joint diseases in the dog: osteochondroses, hip dysplasia, elbow dysplasia''' ''Schlütersche''

Morgan, J. (2000) '''Hereditary bone and joint diseases in the dog: osteochondroses, hip dysplasia, elbow dysplasia''' ''Schlütersche''

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