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===Pathogenesis===

<p>General skin changes ('''endocrine alopecia''') seen with endocrine disease include:

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*Hypotrichosis.

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*[[Hypotrichosis]].

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*Alopecia; usually bilaterally symmetric and non-pruritic.

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*[[Alopecia]]; usually bilaterally symmetric and non-pruritic.

*Remaining coat is dry and dull

*Pigment disturbance.

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*Retained puppy hair coat, endocrine alopecia, decreased dermal elastin and catagen follicles ('''Flame follicles''').

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===='''Excess GH (hypersomatotropism)'''====

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===='''Excess GH ([[hypersomatotropism]])'''====

*Grossly: thick, folded skin on head, neck and extremities, possibly with hypertrichosis

*Microscopically: epidermal hyperplasia, dermal fibrosis, mucinous degeneration of dermis

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====[[Hyperoestrogenism|'''Hyperoestrogenism''']]====

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====[[Hyperoestrogenism - Dog|'''Hyperoestrogenism''']]====

*Grossly: endocrine alopecia, enlarged vulva and abnormal oestrus cycle in females, gynecomastia, pendulous prepuce or enlarged prostate in males

*Microscopically: telogen follicles, hyperkeratosis and acanthosis or epidermis and follicular infundibulum

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*Castration may temporarily remove symptoms

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===='''Superficial Necrolytic Dermatopathy'''====

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===='''[[Superficial Necrolytic Dermatopathy]]'''====

*Also known as ''diabetic dermatopathy, hepatocutaneous syndrome''

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[[Category:Endocrine System - Pathology|A]]

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[[Category:Integumentary System - Pathology]]

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edits

Endocrine effects on the skin - Pathology (view source)