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| − | {{toplink
| + | #redirect[[Intersex#Testicular feminisation]] |
| − | |backcolour =EED2EE
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| − | |linkpage =Reproductive System - Anatomy & Physiology
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| − | |linktext =Reproductive System
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| − | |maplink = Reproductive System (Content Map) - Anatomy & Physiology
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| − | |pagetype =Anatomy
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| − | |sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development
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| − | |subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT
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| − | |sublink2=Fertilisation, Implantation and Early Embryonic Development -Sexual Differentiation- Anatomy & Physiology
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| − | |subtext2=SEXUAL DIFFERENTIATION
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| − | }}
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| − | <br>
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| − | == Aetiology ==
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| − | | |
| − | | |
| − | * Genotype XY as should be in the male.
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| − | * Testes develop normally and secrete Androgens and MIH
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| − | * Foetal genetalia are genetically insensitive to the actions of Androgens due to a point mutation in the Androgen receptor.
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| − | | |
| − | == Consequence ==
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| − | | |
| − | * Wolffian Ducts regress, allowing formation of '''female external genetalia''':
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| − | ** Labia
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| − | ** Clitoris
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| − | ** Vagina
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| − | * Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression.
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| − | * Since both Wolffian AND Mullarian Ducts regress, there is '''no internal genetalia'''.
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