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[[Image:LH Macrophage Histology.jpg|thumb|right|125px|<p>'''Macrophage'''</p><sup>© Nottingham Uni</sup>]]
[[Image:LH Macrophage Histology.jpg|thumb|right|125px|<p>'''Macrophage'''</p><sup>© Nottingham Uni</sup>]]
==Introduction==
==Introduction==
Macrophages are large, round cells that contain a central round nucleus and have abundant clear, often vacuolated, cytoplasm. Macrophages acts as sentinel cells; they have a role in destroying bacteria, protozoa and tumour cells, and release substances that act upon other immune cells. Macrophages are [[Phagocytosis|phagocytic]], long lived and are found throughout the body.
Macrophages are large, round cells that contain a central round nucleus and have abundant clear, often vacuolated, cytoplasm. Macrophages acts as sentinel cells; they have a role in destroying bacteria, protozoa and tumour cells, and release substances that act upon other immune cells. They are also responsible for clearing dead and damaged cells and tissue through the process known as efferocytosis. Macrophages are [[Phagocytosis|phagocytic]], long lived and are found throughout the body.
==Development==
==Development==