Difference between revisions of "Ondansetron"

From WikiVet English
Jump to navigation Jump to search
(Created page with "Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting), often following chemotherapy. It affects both peripheral and ...")
Line 1: Line 1:
#redirect[[Emetics and Anti-Emetic Drugs#5-HT3 Receptor Antagonists]]
+
Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting), often following chemotherapy. It affects both peripheral and central nerves[1]. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone. It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors.
 +
 
 +
http://en.wikipedia.org/wiki/File:Ondansetron_skeletal.svg

Revision as of 23:53, 3 June 2012

Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting), often following chemotherapy. It affects both peripheral and central nerves[1]. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone. It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors.

http://en.wikipedia.org/wiki/File:Ondansetron_skeletal.svg