Difference between revisions of "Yersinia"
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− | + | * Cause [[Intestines - disease due to pathogens|intestinal disease]] | |
+ | |||
+ | ===Overview=== | ||
+ | |||
+ | *Cause disease in animals and are important zoonoses | ||
+ | *10 species of which ''Yersinia pestis, Yersinia pseudotuberculosis amd Yersinia enterocolitica'' are pathogenic to animals and humnans | ||
+ | *Rodents provide a reservoir of ''Yersinia pestis'', which is the cause of human plague; fleas transmit the infection to other animals and humans | ||
+ | *''Yersinia pseudotuberculosis and enterocolitica'' reside in the intestine of domestic and wild animals and birds | ||
+ | *Birds may cause mechanical transfer of the organisms | ||
+ | |||
+ | ===Characteristics=== | ||
+ | |||
+ | *Enterobacteria, but grow more slowly and at lower temperatures than other enterobacteria | ||
+ | *Gram negative, non-spore forming, facultative anaerobes - rods or colibacilli | ||
+ | *Non-lactose fermentors | ||
+ | *Facultative intracellular pathogens | ||
+ | *Show bipolar staining in Giemsa-stained smears from animal tissue | ||
+ | *Pathogenic strains identified by serotyping and biotyping | ||
+ | |||
+ | ===Pathogenesis=== | ||
+ | |||
+ | *Invasive ''Yersinia'' grow inside macrophages | ||
+ | *Survive in phagolysosomes and do not interfere with degranulation or lysosomal fusion | ||
+ | *Resistant to macrophage killing mechanisms | ||
+ | *The bacteria destroy macrophages in lymph nodes, liver and spleen, causing septicaemia | ||
+ | |||
+ | ===Clnical infections=== | ||
+ | |||
+ | ===Diagnosis=== | ||
+ | |||
+ | ===Control=== | ||
+ | |||
+ | ===Treatment=== |
Revision as of 12:46, 9 February 2008
- Cause intestinal disease
Overview
- Cause disease in animals and are important zoonoses
- 10 species of which Yersinia pestis, Yersinia pseudotuberculosis amd Yersinia enterocolitica are pathogenic to animals and humnans
- Rodents provide a reservoir of Yersinia pestis, which is the cause of human plague; fleas transmit the infection to other animals and humans
- Yersinia pseudotuberculosis and enterocolitica reside in the intestine of domestic and wild animals and birds
- Birds may cause mechanical transfer of the organisms
Characteristics
- Enterobacteria, but grow more slowly and at lower temperatures than other enterobacteria
- Gram negative, non-spore forming, facultative anaerobes - rods or colibacilli
- Non-lactose fermentors
- Facultative intracellular pathogens
- Show bipolar staining in Giemsa-stained smears from animal tissue
- Pathogenic strains identified by serotyping and biotyping
Pathogenesis
- Invasive Yersinia grow inside macrophages
- Survive in phagolysosomes and do not interfere with degranulation or lysosomal fusion
- Resistant to macrophage killing mechanisms
- The bacteria destroy macrophages in lymph nodes, liver and spleen, causing septicaemia