Difference between revisions of "Shigella"

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*Not significant cause of infection in domestic animals
 
*Not significant cause of infection in domestic animals
*Causes dysentery in humans and primates
+
*Causes [[Intestines - disease due to pathogens#Dysentery in Humans and Primates|dysentery in humans and primates]]
 
*Enteroinvasive, invading the intestinal mucosa and causing necrosis
 
*Enteroinvasive, invading the intestinal mucosa and causing necrosis
 
*Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
 
*Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
 
*A large plasmid permits survival in cells and is responsible for invasivenss
 
*A large plasmid permits survival in cells and is responsible for invasivenss
*Closely related to [[Escherichia coli|''E. coli'']] - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli''
+
*Closely related to ''E. coli'' - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli''
 
 
* Cause of dysentery in humans and primates.
 
 
 
===Dysentery in Humans and Primates===
 
 
 
* [[Shigella|''Shigella'']] is are enteroinvasive,
 
** Penetrate the intestinal mucosa.
 
** Cause necrosis in patches of mucosa.
 
* [[Shigella|''Shigella'']] do not invade beyond the lamina propria to the bloodstream.
 
* Invasive potential is carried by a large plasmid.
 
** Relates to the ability to survive inside the host cells.
 
* Some strains produce Shiga toxin.
 
** Related to vero cytotoxin of some pathogenic strains of [[Escherichia coli|''E.coli'']].
 
 
 
[[Category:Enterobacteriaceae]]
 
[[Category:Enteritis,_Bacterial]]
 
[[Category:To_Do_-_Bacteria]]
 

Revision as of 14:57, 9 February 2008

  • Not significant cause of infection in domestic animals
  • Causes dysentery in humans and primates
  • Enteroinvasive, invading the intestinal mucosa and causing necrosis
  • Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
  • A large plasmid permits survival in cells and is responsible for invasivenss
  • Closely related to E. coli - some strains produce Shiga toxin which is related to vero cytotoxin of E. coli