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==[[Skin Endocrine Function - Anatomy & Physiology|Endocrinology of the Skin]]==

|linkpage =Integumentary - Anatomy & Physiology

|maplink = Integumentary System (Content Map) - Anatomy & Physiology

 

==Endocrinology of the Skin==

There are various hormones that influence the structure of the [[Skin - Anatomy & Physiology|skin]].  These influences may be made apparent by the repeated long-term administration of various glucocorticoids or their analogues.  Endogenous imbalances are generally seen in adult mature animals although congenital forms have been seen, especially with [[Thyroid Gland - Anatomy & Physiology#Problems associated with the Thyroid Gland|hypothyroidism]].  The hormones implicated as important for maintaining skin structure are '''thyroxine, cortisol''' and '''estradiol'''.  Deficiencies or excessive production may result from abberations in the function of the [[Adrenal Glands - Anatomy & Physiology|hypothalamic-adrenal axis]],  the '''adrenal gland, thyroid gland''' or the '''gonads'''.

There are various hormones that influence the structure of the [[Skin - Anatomy & Physiology|skin]].  These influences may be made apparent by the repeated long-term administration of various glucocorticoids or their analogues.  Endogenous imbalances are generally seen in adult mature animals although congenital forms have been seen, especially with [[Thyroid Gland - Anatomy & Physiology#Problems associated with the Thyroid Gland|hypothyroidism]].  The hormones implicated as important for maintaining skin structure are '''thyroxine, cortisol''' and '''estradiol'''.  Deficiencies or excessive production may result from abberations in the function of the [[Adrenal Glands - Anatomy & Physiology|hypothalamic-adrenal axis]],  the '''adrenal gland, thyroid gland''' or the '''gonads'''.

==Nutrition and the Skin==

==Nutrition and the Skin==

Most animals are fed balanced diets and are therefore unlikely to exhibit symptoms.  There are some systemic conditions that can reflect deficiency as a result of [[Liver General Pathology - Pathology|hepatic]] or [[Small and Large Intestines - Pathology|intestinal]] diseases for example.

Most animals are fed balanced diets and are therefore unlikely to exhibit symptoms.  There are some systemic conditions that can reflect deficiency as a result of [[:Category:Liver - General Pathology|hepatic]] or [[Intestines, Small and Large - Pathology|intestinal]] diseases for example.

Malnutrition whether due to a deficiency of protein or other nutrients or secondary to a debilitating condition may lead to a dull, brittle and thin [[Hair - Anatomy & Physiology|haircoat]] and to dry, scaly [[Skin - Anatomy & Physiology|skin]].  This in part reflects the high requirement for dietary amino acids to supply requisite building blocks for epidermal turnover and hair growth. Sulfur-containing amino acids are common in the skin and therefore sulfur supplementation is popular for dealing with skin conditions.

Malnutrition whether due to a deficiency of protein or other nutrients or secondary to a debilitating condition may lead to a dull, brittle and thin [[Hair - Anatomy & Physiology|haircoat]] and to dry, scaly [[Skin - Anatomy & Physiology|skin]].  This in part reflects the high requirement for dietary amino acids to supply requisite building blocks for epidermal turnover and hair growth. Sulfur-containing amino acids are common in the skin and therefore sulfur supplementation is popular for dealing with skin conditions.

*'''Vitamin C''' deficiency may be associated with [[Skin Nutritional - Pathology|scurvy]] in guinea pigs.  The impact of various disease processes that influence feed intake may lead to poor quality coat and skin condition.

*'''Vitamin C''' deficiency may be associated with [[Skin Nutritional - Pathology|scurvy]] in guinea pigs.  The impact of various disease processes that influence feed intake may lead to poor quality coat and skin condition.

*'''Vitamin D''' is processed in part in the skin.

*'''[[Vitamin D]]''' is processed in part in the skin.