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| **Infection via inhalation, wounds or teat canal; also ingestion | | **Infection via inhalation, wounds or teat canal; also ingestion |
| **Causes granulomatous lesions in animals | | **Causes granulomatous lesions in animals |
− | **Canine nocardiosis: cutaneous pyogranulomas; [[Peritoneal cavity - inflammatory#In dogs|peritonitis]]; [[Bacterial infections#Nocardiosis|pleuritis]] and pyothorax; disseminated lesions | + | **Canine nocardiosis: |
| + | ***Thoracic, cutaneous and disseminated forms |
| + | ***Cutaneous pyogranulomas: ulcers or granulomatous swellings with discharging fistulae |
| + | ***[[Peritoneal cavity - inflammatory#In dogs|peritonitis]] |
| + | ***[[Bacterial infections#Nocardiosis|pleuritis]] and pyothorax with fever, anorexia and respiratory distress |
| + | ***Disseminated lesions |
| + | ***Treat with appropriate systemic antibiotics for 6 weeks |
| **Cattle: chronic mastitis; abortion | | **Cattle: chronic mastitis; abortion |
| **Pigs: abortion | | **Pigs: abortion |
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| **Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes | | **Superoxide dismutase and catalase as well as a thick peptidoglycan wall prevent activity of phagocytes |
| **Chronic, progressive disease | | **Chronic, progressive disease |
| + | **Positive modified Ziehl-Neelson |
| + | **Culture on blood agar and incubate under aerobic conditions at 37 degrees centigrade for 10 days |
| + | **White, powdery colonies, adherent to the agar appear after 5 days |
| + | **Subculture onto Sabouraud dextrose agar yields wrinkled, orange colonies |
| **Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins) | | **Lesions difficult to treat due to resistance of organisms to many antimicrobials (e.g. penicillins) |
| **Cell-mediated immunity required | | **Cell-mediated immunity required |
− | *''Nocardia farcinica'' causes bovine farcy | + | *''Nocardia farcinica'' causes bovine farcy, a chronic infection of superficial lymphatic vessels and lymph nodes |
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