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Also known as: '''''Canine Distemper — CDV'''''

|Also known as:

|'''Canine Distemper''' <BR> '''CDV'''

==Description==

==Description==

Dogs suffering distemper should be treated in isolation with barrier nursing to prevent spread to other dogs. Treatment is supportive, including intravenous fluid therapy to correct the deficit cause by vomiting and diarrhoea and antiobitics to reduce secondary infections. Anticonvulsants such as phenobarbital and potassium bromide may be necessary to control seizures. Although corticosteroids may alleviate clinical signs in the short term, they should be used with caution as they augment the immunosuppression caused by CDV and may enhance viral dissemination. Animals should be rested and fed a diet appropriate to the severity of their gastrointestinal signs.

Dogs suffering distemper should be treated in isolation with barrier nursing to prevent spread to other dogs. Treatment is supportive, including intravenous fluid therapy to correct the deficit cause by vomiting and diarrhoea and antiobitics to reduce secondary infections. Anticonvulsants such as phenobarbital and potassium bromide may be necessary to control seizures. Although corticosteroids may alleviate clinical signs in the short term, they should be used with caution as they augment the immunosuppression caused by CDV and may enhance viral dissemination. Animals should be rested and fed a diet appropriate to the severity of their gastrointestinal signs.

[[Vaccination]] is key to controlling canine distemper. Modified live vaccines are available, and are considered a "core" vaccination for dogs. Puppies can receive their first vaccination between 6 and 8 weeks of age, and must be given at least two doses of CDV vaccine with the final does being administered after 12 weeks of age. This multiple dose regimen is necessary because the maternal antibody in puppies greatly hampers the efficacy of vaccination by neutralising viral antigen. Modified live vaccines should not be used in pregnant bitches, and may cause fatal disease in certain wildlife species. Therefore a killed vaccine is available for use in, for example, red pandas.

[[Vaccines|Vaccination]] is key to controlling canine distemper. Modified live vaccines are available, and are considered a "core" vaccination for dogs. Puppies can receive their first vaccination between 6 and 8 weeks of age, and must be given at least two doses of CDV vaccine with the final does being administered after 12 weeks of age. This multiple dose regimen is necessary because the maternal antibody in puppies greatly hampers the efficacy of vaccination by neutralising viral antigen. Modified live vaccines should not be used in pregnant bitches, and may cause fatal disease in certain wildlife species. Therefore a killed vaccine is available for use in, for example, red pandas.

==Prognosis==

==Prognosis==

The prognosis for CDV infection is dependent on the strain of the virus and the host immune response, as infection may be subclinical, subacute or acute. Overall, the mortality rate is around 50%, with death occuring 2 weeks to 3 months post-infection. Animals that appear to recover from early systemic signs may go on to develop CNS involvement which can vary in severity. Euthanasia may be considered with the onset of neurological signs, and is indicated when seizuring is uncontrollable. Dogs that fully recover do not shed the virus.

The prognosis for CDV infection is dependent on the strain of the virus and the host immune response, as infection may be subclinical, subacute or acute. Overall, the mortality rate is around 50%, with death occuring 2 weeks to 3 months post-infection. Animals that appear to recover from early systemic signs may go on to develop CNS involvement which can vary in severity. Euthanasia may be considered with the onset of neurological signs, and is indicated when seizuring is uncontrollable. Dogs that fully recover do not shed the virus.

==Links==

==Links==

#Beineke, A, Puff, C, Seehusen, F, Baumgartner, W (2009) Pathogenesis and immunopathology of systemic and nervous canine distemper. ''Veterinary Immunology and Immunopathology'', '''127''', 1-18.

#Beineke, A, Puff, C, Seehusen, F, Baumgartner, W (2009) Pathogenesis and immunopathology of systemic and nervous canine distemper. ''Veterinary Immunology and Immunopathology'', '''127''', 1-18.

[[Category:Morbilliviruses]][[Category:Dog]]

 

[[Category:To_Do_- Lizzie]] [[Category:To_Do_- Review]]

 

 

[[Category:Morbilliviruses]][[Category:Respiratory Diseases - Dog]][[Category:Dog Viruses]]

[[Category:Expert Review]]

[[Category:Respiratory Viral Infections]]

[[Category:Respiratory Viral Infections]]