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*[[Respiratory Bacterial Infections - Pathology#Contagious bovine pleuropneumonia (CBPP)|Contagious bovine pleuropneumonia]] is caused by ''M. mycoides'' subsp. ''mycoides'' small colony type

*A severe contagious disease of cattle

*Endemic in Africa, the Middle East and Asia

*Aerosol transmission by close contact with clinically or subclinically affected animals

*Severity depends on strain and host susceptibility

*50% morbidity; mortality rate high in severe outbreaks

[[Image:Contagious bovine pleuropneumonia.jpg|right|thumb|200px|<small><center>Contagious bovine pleuropneumonia (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

''M.mycoides'' is a species of the ''[[Mycoplasmas species - Overview|Mycoplasmas]]'' genus. The subsp. ''mycoides'' causes Contagious Bovine Pleuropneumonia (CBPP), a severe contagious respiratory disease of cattle that is endemic in Africa, the Middle East and Asia. It is notifiable in the UK and many other countries and has not been seen here for many years. It is transmitted by close contact with clinically or subclinically affected animals and severity depends on strain and host susceptibility. There is usually around 50% morbidity and high mortality rate in severe outbreaks.

*Clinical signs

== Clinical Signs  ==

Clinical signs include an acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal discharge, which all occur suddenly. Dyspnoea occurs with abducted elbows and extended necks and an expiratory grunt. The disease can be fatal within 1-3 weeks.

**Marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas

Calves may suffer from [[Infectious Arthritis#In_Cattle|arthritis]], synovitis and [[Endocarditis|endocarditis]], but are most commonly seen as sudden death.

**Clinical signs and post-mortem appearance

**PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid

**Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA

*''M. mycoides'' subsp. 'mycoides'' causes septicaemia, pleuropneumonia, arthritis and mastitis in goats

A PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage of fluids is useful, as is fluorescent antibody test or serological tests such as serum agglutination, haemagglutination, complement fixation and [[ELISA testing|ELISA]]. Due to the rarity of the disease in developed countries, the best diagnostic tool is not known.

**Vaccination in endemic regions[[Category:Mycoplasmas]][[Category:Cattle]]

[[Category:Goat]]

 

Slaughter of affected cattle in countries where the disease is exotic is necessary by law. Movement restrictions, quarantine and slaughter of carrier animals in endemic countries is required. Vaccination has been used in endemic regions.

 

 

 

 

 

 

 

 

[[Category:Respiratory_Diseases_-_Cattle]] [[Category:Respiratory_Bacterial_Infections]]

[[Category:Expert_Review - Farm Animal]]

[[Category:Mycoplasmas]]