Difference between revisions of "Labrador with changed appearance"

Revision as of 11:01, 15 August 2012

51

THIS CASE WAS PROVIDED BY....... Elsevier Health Sciences - North and Banks, Small Animal Oncology

Signalment: 9-year-old male neutered Labrador Retriever

Chief complaint: for the last three months he had not been eating well at home and would not eat dry food so the clients had changed him to tinned food. Two weeks ago the clients noticed the change in him that led to this consultation.

Physical Examination:

1

What did you find question, based on the photograph, when you examined this dog?

2

What cranial nerve innervates this muscle?

3

You examine the dog further and can feel a large mass located at the caudal part of the ramus of the mandible. When you open his mouth you see a large tumour. What is the most common oral tumour seen in the dog?

4

Based on your knowledge of oral tumours which of the above carries the best prognosis (i) and which carries the worst prognosis (ii)?

5

What do you recommend to your client?

	Do nothing. This tumour is large and must have invaded the temporal muscles.
	Advise an incisional biopsy and computed tomography (CT) scan to determine the extent of the tumour.
	Excise what you can from the inside of the mouth.
	Recommend palliative care and send him home on non-steroidal anti-inflammatory drugs (NSAIDs).
	That irrespective of a biopsy the prognosis is poor and you would have to remove his dog’s jaw.
Please select an option Incorrect. You have made a judgement without attempting to evaluate your patient. Understandably your client is not satisfied and goes for a second opinion. Correct Incorrect. That would not benefit your patient and would literally just make a mess. Your client decides to get a second opinion. Incorrect. Your client wants to know if anything further can be done for his dog and therefore seeks a second opinion. Incorrect. You need a better idea of the extent of the tumour and exactly what it is before deciding on options.

Histopathlogy report
Stratified squamous epithelium covering the tissue is ulcerated. The epithelial tissue is proliferative and contiguous in places with a mass present below. The underlying collagen is infiltrated by a solid mass of proliferating squamous epithelial tissue. The epithelial tissue occurs as masses, trabeculae or nests with minimal stromal tissue. The epithelial cells are variable in size; they have large nuclei with prominent nucleoli; mitotic figures are frequent.

6

Your client went ahead with the CT scan and biopsy and now wants to know what you found. The biopsy report is available for you to examine but unfortunately the diagnosis is missing so you will have to interpret it for your client. Review the Histopathology report and make your diagnosis.

7

You next review the CT scan. What are your findings based on the scan?

8

What is the treatment of choice for oral squamous cell carcinoma in the dog?

	Removal of tumour with underlying bone (mandibulectomy/maxillectomy) with adequate margins.
	Carboplatin chemotherapy
	Radiation
	Palliative therapy with NSAIDs
	Photodynamic therapy
Please select an option Correct. Incorrect. Your client is unhappy with your knowledge of his dog’s condition. You can review the chapter on oral tumours in North and Banks, Small Animal Oncology. Incorrect. Your client is unhappy with your knowledge of his dog’s condition. You can review the chapter on oral tumours in North and Banks, Small Animal Oncology. Incorrect. Your client is unhappy with your knowledge of his dog’s condition. You can review the chapter on oral tumours in North and Banks, Small Animal Oncology. Incorrect. Your client is unhappy with your knowledge of his dog’s condition. You can review the chapter on oral tumours in North and Banks, Small Animal Oncology.

9

The problem in this case is that the tumour is extremely large and located caudally so even with a hemimandibulectomy medial margins would not be achieved and adjuvant radiation would be required. Your client is concerned about such a large surgery and wants to know if there are any alternative options. Can you suggest another option?

10

It was decided to go ahead with a course of neoadjuvant radiotherapy with the goal of shrinking the tumour to reduce surgical dose. Before starting treatment however it is important to complete staging. What is required to stage this patient fully?

11

You now review the contrast-enhanced thoracic CT scan. Based on the image, what do you tell your client?

	The CT scan is normal and there are no visible secondaries in the lungs.
	There are metastatic nodules throughout the lungs and nothing further can be done.
	There are metastatic nodules in the lungs but they will grow slowly so treatment for the oral tumour should go ahead anyway.
	There are metastatic nodules in the lungs but they will be treated with chemotherapy.
	The scan shows evidence of pulmonary fibrosis so the patient has a second serious medical problem.
Please select an option Correct. Incorrect. Unfortunately your client takes your advice and euthanizes his dog. Incorrect. Your client is concerned that he would be putting the animal through a lot but wouldn’t have very long because of the metastasis and so decides on euthanasia. Incorrect. Your client is concerned that he would be putting the animal through a lot but wouldn’t have very long because of the metastasis and so decides on euthanasia. Incorrect. Your client is concerned that he would be putting the animal through a lot but wouldn’t have very long because of the metastasis and so decides on euthanasia.

12

13

14

15

16

@@ Line 1: / Line 1: @@
-<b><big>
+<center><WikiQuiz
-<u>Signalment</u>:
+questionnumber="51"
-:9-year-old male neutered Labrador Retriever
+question=""
+choice1=""
+choice2=""
+choice3=""
+choice4=""
+choice5=""
+correctchoice="3"
+feedback1=""
+feedback2=""
+feedback3=""
+feedback4=""
+feedback5=""
+image= "">
+</WikiQuiz></center>
+THIS CASE WAS PROVIDED BY.......
+Elsevier Health Sciences - [http://www.elsevierhealth.co.uk/product.jsp?isbn=9780702042508 North and Banks, Small Animal Oncology]
+Signalment: 9-year-old male neutered Labrador Retriever
+Chief complaint: for the last three months he had not been eating well at home and would not eat dry food so the clients had changed him to tinned food. Two weeks ago the clients noticed the change in him that led to this consultation.
+Physical Examination:
-<u>Chief complaint</u>:
-:For the last three months he had not been eating well at home and would not eat dry food so the clients had changed him to tinned food. Two weeks ago the clients noticed the change in him that led to this consultation.
-</big></b>
-<br><br>
 <center><WikiQuiz
 questionnumber="1"
@@ Line 94: / Line 111: @@
 {| class="mw-collapsible mw-collapsed wikitable"
-! Histopathology report
+! Histopathlogy report
 |-
 | Stratified squamous epithelium covering the tissue is ulcerated. The epithelial tissue is proliferative and contiguous in places with a mass present below. The underlying collagen is infiltrated by a solid mass of proliferating squamous epithelial tissue. The epithelial tissue occurs as masses, trabeculae or nests with minimal stromal tissue. The epithelial cells are variable in size; they have large nuclei with prominent nucleoli; mitotic figures are frequent.
@@ Line 203: / Line 220: @@
 <center><WikiQuiz
 questionnumber="12"
-question="Why would an excisional lymph node biopsy of the submandibular lymph node be superior to a fine-needle aspirate?"
+question=""
-choice1="A. Squamous cell carcinoma often causes local inflammation resulting in enlarged lymph nodes; it is important to rule out reactive versus neoplastic."
+choice1=""
-choice2="B. It is unlikely that the lymph node would be positive so it doesn’t really make any difference. "
+choice2=""
-choice3="C. A biopsy is always more accurate because early metastatic cells can be missed on cytology. "
+choice3=""
-choice4="D. Both A and C are correct "
+choice4=""
-choice5="E. Neither would be appropriate because the sentinel node in this location would be the retropharyngeal node. "
+choice5=""
-correctchoice="4"
+correctchoice="3"
-feedback1="'''Incorrect'''. Choose again."
+feedback1=""
-feedback2="'''Incorrect'''."
+feedback2=""
-feedback3="'''Incorrect'''. Choose again."
+feedback3=""
-feedback4="'''Correct'''."
+feedback4=""
-feedback5="'''Incorrect'''. Choose again."
+feedback5=""
 image= "">
 </WikiQuiz></center>
 <center><WikiQuiz
 questionnumber="13"
-question="Radiotherapy went well and the tumour shrank, permitting a reduced surgical dose. The patient underwent a caudal mandibulectomy. What is the most common acute side-effect of irradiating the oral cavity?"
+question=""
-choice1="Vomiting"
+choice1=""
-choice2="Tooth decay "
+choice2=""
-choice3="Mucositis "
+choice3=""
-choice4="Fibrosis "
+choice4=""
-choice5="Thinning of cortical bone "
+choice5=""
 correctchoice="3"
-feedback1="'''Incorrect'''. Choose again."
+feedback1=""
-feedback2="'''Incorrect'''. Choose again."
+feedback2=""
-feedback3="Correct"
+feedback3=""
-feedback4="'''Incorrect'''. Choose again."
+feedback4=""
-feedback5="'''Incorrect'''. Choose again."
+feedback5=""
 image= "">
 </WikiQuiz></center>
 <center><WikiQuiz
 questionnumber="14"
-question="What is the most common delayed effect of irradiating the oral cavity?"
+question=""
-choice1="Bone necrosis"
+choice1=""
-choice2="Gingival recession"
+choice2=""
-choice3="Tooth loss "
+choice3=""
-choice4="Fibrosis of the tongue "
+choice4=""
-choice5="Skin necrosis "
+choice5=""
-correctchoice="2"
+correctchoice="3"
-feedback1="'''Incorrect'''. Choose again."
+feedback1=""
-feedback2="Correct"
+feedback2=""
-feedback3="'''Incorrect'''. Choose again."
+feedback3=""
-feedback4="'''Incorrect'''. Choose again."
+feedback4=""
-feedback5="'''Incorrect'''. Choose again."
+feedback5=""
 image= "">
 </WikiQuiz></center>
 <center><WikiQuiz
 questionnumber="15"
-question="In view of the successful elimination of the primary, what do you consider the patient’s long-term prognosis to be?"
+question=""
-choice1="Excellent - he should be cured. "
+choice1=""
-choice2="Very good - the risk of local recurrence or metastatic spread is low. "
+choice2=""
-choice3="Good - he may develop metastatic spread, but not for years. "
+choice3=""
-choice4="Fair - this was a large tumour that had been present for months before detection so recurrence or metastatic spread is still a possibility. "
+choice4=""
-choice5="Poor - he would be unlikely to live more than 6 months. "
+choice5=""
-correctchoice="4"
+correctchoice="3"
-feedback1="'''Incorrect'''. This is what we would hope but local recurrence or metastatic spread is still a possibility."
+feedback1=""
-feedback2="'''Incorrect'''. This is what we would hope but local recurrence or metastatic spread is still a possibility."
+feedback2=""
-feedback3="'''Incorrect'''. This is what we would hope but local recurrence or metastatic spread is still a possibility."
+feedback3=""
-feedback4="'''Correct'''."
+feedback4=""
-feedback5="'''Incorrect'''. He should have a better prospect than 6 months."
+feedback5=""
 image= "">
 </WikiQuiz></center>
 <center><WikiQuiz
 questionnumber="16"
-question="Your client had a cat that had exactly the same problem and he wants to know if she could have had the same treatment. What do you tell your client about oral squamous cell carcinoma in the cat?"
+question=""
-choice1="The cat could have had neoadjuvant radiation followed by a caudal mandibulectomy with the same outcome. "
+choice1=""
-choice2="We never perform mandibulectomies on cats because they will not tolerate them. "
+choice2=""
-choice3="Oral squamous cell carcinoma of the mandible of the cat is very sensitive to radiation so radiation is the sole treatment. "
+choice3=""
-choice4="Oral squamous cell carcinoma of the cat does not respond well to radiation and the results have been poor with conventional protocols. "
+choice4=""
-choice5="Cats do not get mandibular squamous cell carcinoma; it is always sublingual. "
+choice5=""
-correctchoice="4"
+correctchoice="3"
-feedback1="'''Incorrect'''. Review oral squamous cell carcinoma in the cat."
+feedback1=""
-feedback2="'''Incorrect'''. Review oral squamous cell carcinoma in the cat."
+feedback2=""
-feedback3="'''Incorrect'''. Review oral squamous cell carcinoma in the cat."
+feedback3=""
-feedback4="'''Correct'''."
+feedback4=""
-feedback5="'''Incorrect'''. Review oral squamous cell carcinoma in the cat."
+feedback5=""
 image= "">
 </WikiQuiz></center>
-<center><WikiQuiz
-questionnumber="17"
-question="Currently, what is the treatment of choice for cats with oral squamous cell carcinoma?"
-choice1="Early detection while surgery is still an option "
-choice2="Mitoxantrone chemotherapy "
-choice3="Approved NSAID"
-choice4="Prednisolone"
-choice5="Cisplatin chemotherapy"
-correctchoice="1"
-feedback1="'''Correct'''."
-feedback2="'''Incorrect'''. Q15&17 are general knowledge questions and do not relate to your ability to manage your patient."
-feedback3="'''Incorrect'''. Q15&17 are general knowledge questions and do not relate to your ability to manage your patient."
-feedback4="'''Incorrect'''. Q15&17 are general knowledge questions and do not relate to your ability to manage your patient."
-feedback5="'''Incorrect'''. Q15&17 are general knowledge questions and do not relate to your ability to manage your patient."
-image= "">
-</WikiQuiz></center>
-<br><br>
-{{Elsevier
-|url = http://www.elsevierhealth.co.uk/product.jsp?isbn=9780702042508
-|book = North and Banks, Small Animal Oncology
-|image = North and Banks SA Oncology.jpg
-}}
-[[Category:Case-based Quizzes]]

Difference between revisions of "Labrador with changed appearance"

Revision as of 11:01, 15 August 2012

Navigation menu

Search