Difference between revisions of "Labrador with changed appearance"
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+ | THIS CASE WAS PROVIDED BY....... | ||
+ | Elsevier Health Sciences - [http://www.elsevierhealth.co.uk/product.jsp?isbn=9780702042508 North and Banks, Small Animal Oncology] | ||
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+ | Signalment: 9-year-old male neutered Labrador Retriever | ||
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+ | Chief complaint: for the last three months he had not been eating well at home and would not eat dry food so the clients had changed him to tinned food. Two weeks ago the clients noticed the change in him that led to this consultation. | ||
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+ | Physical Examination: | ||
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| Stratified squamous epithelium covering the tissue is ulcerated. The epithelial tissue is proliferative and contiguous in places with a mass present below. The underlying collagen is infiltrated by a solid mass of proliferating squamous epithelial tissue. The epithelial tissue occurs as masses, trabeculae or nests with minimal stromal tissue. The epithelial cells are variable in size; they have large nuclei with prominent nucleoli; mitotic figures are frequent. | | Stratified squamous epithelium covering the tissue is ulcerated. The epithelial tissue is proliferative and contiguous in places with a mass present below. The underlying collagen is infiltrated by a solid mass of proliferating squamous epithelial tissue. The epithelial tissue occurs as masses, trabeculae or nests with minimal stromal tissue. The epithelial cells are variable in size; they have large nuclei with prominent nucleoli; mitotic figures are frequent. | ||
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Revision as of 11:20, 15 August 2012
51 |
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THIS CASE WAS PROVIDED BY....... Elsevier Health Sciences - North and Banks, Small Animal Oncology
Signalment: 9-year-old male neutered Labrador Retriever
Chief complaint: for the last three months he had not been eating well at home and would not eat dry food so the clients had changed him to tinned food. Two weeks ago the clients noticed the change in him that led to this consultation.
Physical Examination:
1 |
What did you find question, based on the photograph, when you examined this dog? |
2 |
What cranial nerve innervates this muscle? |
3 |
You examine the dog further and can feel a large mass located at the caudal part of the ramus of the mandible. When you open his mouth you see a large tumour. What is the most common oral tumour seen in the dog? |
4 |
Based on your knowledge of oral tumours which of the above carries the best prognosis (i) and which carries the worst prognosis (ii)? |
5 |
What do you recommend to your client? |
Histopathlogy report |
---|
Stratified squamous epithelium covering the tissue is ulcerated. The epithelial tissue is proliferative and contiguous in places with a mass present below. The underlying collagen is infiltrated by a solid mass of proliferating squamous epithelial tissue. The epithelial tissue occurs as masses, trabeculae or nests with minimal stromal tissue. The epithelial cells are variable in size; they have large nuclei with prominent nucleoli; mitotic figures are frequent. |
6 |
Your client went ahead with the CT scan and biopsy and now wants to know what you found. The biopsy report is available for you to examine but unfortunately the diagnosis is missing so you will have to interpret it for your client. Review the Histopathology report and make your diagnosis. |
7 |
You next review the CT scan. What are your findings based on the scan? |
8 |
What is the treatment of choice for oral squamous cell carcinoma in the dog? |
9 |
The problem in this case is that the tumour is extremely large and located caudally so even with a hemimandibulectomy medial margins would not be achieved and adjuvant radiation would be required. Your client is concerned about such a large surgery and wants to know if there are any alternative options. Can you suggest another option? |
10 |
It was decided to go ahead with a course of neoadjuvant radiotherapy with the goal of shrinking the tumour to reduce surgical dose. Before starting treatment however it is important to complete staging. What is required to stage this patient fully? |
11 |
You now review the contrast-enhanced thoracic CT scan. Based on the image, what do you tell your client? |
12 |
Why would an excisional lymph node biopsy of the submandibular lymph node be superior to a fine-needle aspirate? |
13 |
Radiotherapy went well and the tumour shrank, permitting a reduced surgical dose. The patient underwent a caudal mandibulectomy. What is the most common acute side-effect of irradiating the oral cavity? |
14 |
What is the most common delayed effect of irradiating the oral cavity? |
15 |
In view of the successful elimination of the primary, what do you consider the patient’s long-term prognosis to be? |
16 |
Your client had a cat that had exactly the same problem and he wants to know if she could have had the same treatment. What do you tell your client about oral squamous cell carcinoma in the cat? |