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Post mortem findings include; a shiny appearance of the serosa of the spiral colon, which will also be turgid and oedematous. Haemorrhage is sometimes seen. Characteristically in this disease, the small intestine is not affected. Fibrinous deposits are seen on the mucosa as the disease progresses and the mucosa underneath is eroded to expose blood vessels in lamina propria.
 
Post mortem findings include; a shiny appearance of the serosa of the spiral colon, which will also be turgid and oedematous. Haemorrhage is sometimes seen. Characteristically in this disease, the small intestine is not affected. Fibrinous deposits are seen on the mucosa as the disease progresses and the mucosa underneath is eroded to expose blood vessels in lamina propria.
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Samples can be taken to perform silver stains to show organisms in the epithelium of the mucosa. The bacteria can also be cultured on blood agar with added antibiotics for at least 3 days - ''B. hyodysenteriae'' causes complete haemolysis whereas other spirochaetes cause partial haemolysis.
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Samples can be taken to perform silver stains to show organisms in the epithelium of the mucosa. The bacteria can also be cultured on blood agar with added antibiotics for at least 3 days - ''B. hyodysenteriae'' causes complete haemolysis whereas other spirochaetes cause partial haemolysis. This is called a "strong beta" reaction, where complete beta hemolysis is visible, especially after removing a plug of agar.  This is called a ring phenomenon and is indicative of a pathogenic Brachyspira infection. 
    
Immunofluorescence, DNA probes and biochemical tests can also be used though this is usually not cost effective. Serology using ELISA can be used on a herd basis as well as PCR, immunofluorescence or electron microscopy.
 
Immunofluorescence, DNA probes and biochemical tests can also be used though this is usually not cost effective. Serology using ELISA can be used on a herd basis as well as PCR, immunofluorescence or electron microscopy.
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