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==Hypothalamus==
 
==Hypothalamus==
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The hypothalamus is a small area in the ventral diencephalon of the [[Forebrain - Anatomy & Physiology|forebrain]], in the floor of the third ventricle, and is a functional link between the [[Nervous and Special Senses - Anatomy & Physiology#Nervous System|nervous]] and [[Endocrine System Overview - Anatomy & Physiology|endocrine]] systems.
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The hypothalamus controls most of the [[Endocrine System Overview - Anatomy & Physiology|endocrine glands]] within the body, largely through stimulation of the [[Pituitary Gland - Anatomy & Physiology|Pituitary Gland]] by secretion of [[Hormones - Anatomy & Physiology#Classifications of Hormones|neurohormones]]. It is a vital regulator of homeostasis, including [[Thermoregulation - Anatomy & Physiology| Thermoregulation]]. Further information on the physiology of the hypothalamus can be found [[Hypothalamus - Anatomy & Physiology|here]].
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==Pituitary Gland==
 
==Pituitary Gland==
 
The pituitary gland, or '''hypophysis''' is an elongated appendage of the brain lying within a bony cavity of the [[Skull and Facial Muscles - Anatomy & Physiology#Sphenoid Bone (os sphenoidale)|sphenoid bone]] in the base of the skull - the '''Sella Turcica'''. The hypophysis is suspended ventral to the the [[Hypothalamus - Anatomy & Physiology|hypothalamus]] by a thin '''infundibular stalk'''. It lies between the more rostral '''optic chiasma''', and the more caudal '''mammillary bodies''', separated from the brain by a fold of dura mater known as the '''diaphragma sellae'''.  The gland is divided into '''anterior and posterior''', with different embryological origins reflecting a difference in function.
 
The pituitary gland, or '''hypophysis''' is an elongated appendage of the brain lying within a bony cavity of the [[Skull and Facial Muscles - Anatomy & Physiology#Sphenoid Bone (os sphenoidale)|sphenoid bone]] in the base of the skull - the '''Sella Turcica'''. The hypophysis is suspended ventral to the the [[Hypothalamus - Anatomy & Physiology|hypothalamus]] by a thin '''infundibular stalk'''. It lies between the more rostral '''optic chiasma''', and the more caudal '''mammillary bodies''', separated from the brain by a fold of dura mater known as the '''diaphragma sellae'''.  The gland is divided into '''anterior and posterior''', with different embryological origins reflecting a difference in function.
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===Pars Intermedia===
 
===Pars Intermedia===
 
This is the residual lumen of '''Rathke's Pouch''' and consists of a series of small cystic cavities (follicles filled with colloid), with both basophillic and chromatophobic (poorly staining) cell types. These extend into the '''pars nervosa'''.T The pars intermedia separates the anterior and posterior lobes. Endocrine cells in this region are known as '''melanotropes'''. These  convert the [[Prohormones - Anatomy & Physiology|prohormone]] '''pro-opiomelanocorticotropin''' (POMC) to '''melanocyte stimulating hormone''' (a-MSH) and '''corticotropin-like intermediate lobe peptide''' (CLIP). The pars intermedia is innervated by dopaminergic neurones originating in the periventricular nucleus of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]].
 
This is the residual lumen of '''Rathke's Pouch''' and consists of a series of small cystic cavities (follicles filled with colloid), with both basophillic and chromatophobic (poorly staining) cell types. These extend into the '''pars nervosa'''.T The pars intermedia separates the anterior and posterior lobes. Endocrine cells in this region are known as '''melanotropes'''. These  convert the [[Prohormones - Anatomy & Physiology|prohormone]] '''pro-opiomelanocorticotropin''' (POMC) to '''melanocyte stimulating hormone''' (a-MSH) and '''corticotropin-like intermediate lobe peptide''' (CLIP). The pars intermedia is innervated by dopaminergic neurones originating in the periventricular nucleus of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]].
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This region of the hypothalamus is clinically important in horses. For more information see [[Equine Pituitary Pars Intermedia Dysfunction|Equine pituitary pars intermedia dysfunction]].
    
==Thyroid Gland==
 
==Thyroid Gland==
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The pineal gland secretes [[Melatonin|melatonin]] in response to day length. The retina detects day length and sends an impulse via the [[Hypothalamus - Anatomy & Physiology|hypothalamus]], thoracic [[Spinal Cord - Anatomy & Physiology|spinal cord]] and cranial cervical ganglia to the pineal gland. The gland effectively acts as the body's '''biological clock''' and helps regulate the circadian rhythm, sleep and the seasonal and diurnal variations in [[:Category:Reproductive Behaviour|reproductive behaviour]]. In the horse,melatonin is inbitory on gonad function via its antigonadotrophic effects. Melatonin production is inhibited by light, therefore melatonin levels decrease in spring making horses 'long day breeders'.
 
The pineal gland secretes [[Melatonin|melatonin]] in response to day length. The retina detects day length and sends an impulse via the [[Hypothalamus - Anatomy & Physiology|hypothalamus]], thoracic [[Spinal Cord - Anatomy & Physiology|spinal cord]] and cranial cervical ganglia to the pineal gland. The gland effectively acts as the body's '''biological clock''' and helps regulate the circadian rhythm, sleep and the seasonal and diurnal variations in [[:Category:Reproductive Behaviour|reproductive behaviour]]. In the horse,melatonin is inbitory on gonad function via its antigonadotrophic effects. Melatonin production is inhibited by light, therefore melatonin levels decrease in spring making horses 'long day breeders'.
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[[Category:To Do - AP Review]]
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[[Category:Horse Anatomy]]
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