Difference between revisions of "Brucella species"
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| − | # | + | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> |
| + | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | ||
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| + | *''B. abortus'' occasionally in [[Joints - inflammatory#In Cattle|arthritis of cattle]] | ||
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| + | *Isolated from closed cases of [[Bursae and Tendons - inflammatory#Poll Evil and Fistulous Withers|Poll Evil and Fistulous Withers]] | ||
| + | |||
| + | ===Overview=== | ||
| + | |||
| + | *Important zoonoses worldwide | ||
| + | *Cause chronic granulomatous diseases | ||
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| + | |||
| + | ===Characteristics=== | ||
| + | |||
| + | *Small, non-moltile, Gram negative coccobacilli | ||
| + | *Facultatice intracellular pathogens | ||
| + | |||
| + | *6 species | ||
| + | |||
| + | ===Pathogenesis and pathogenicity=== | ||
| + | |||
| + | *Penetrate nasal, oral or pharyngeal mucosa | ||
| + | *Phagocytosed and carried to regional lymph nodes | ||
| + | *Survive and multiply in cells of the reticulo-endothelial system | ||
| + | *Inhibit lysosome-phagosome fusion | ||
| + | *Lymph nodes enlarge (lymphatic and lymphoreticular hyperplasia) and inflammation is induced | ||
| + | *Surviving organisms spread to other organs (liver, spleen, placenta) and cause granulomatous reactions | ||
| + | *Eythritol is a growth stimulant and attracts the bacteria to the bovine placenta | ||
| + | *Infection of foetus and abortion | ||
| + | |||
| + | |||
| + | ===Clinical disease=== | ||
| + | |||
| + | |||
| + | |||
| + | |||
| + | ===Diagnosis=== | ||
| + | |||
| + | |||
| + | |||
| + | |||
| + | ===Control=== | ||
| + | |||
| + | *Serological testing of milk (Milk Ring Test) and beef cattle (Rose Bengal Plate Test) | ||
| + | *Serological tests detect anti-lipopolysaccharide antibodies | ||
Revision as of 16:59, 17 May 2008
- B. abortus occasionally in arthritis of cattle
- Isolated from closed cases of Poll Evil and Fistulous Withers
Overview
- Important zoonoses worldwide
- Cause chronic granulomatous diseases
Characteristics
- Small, non-moltile, Gram negative coccobacilli
- Facultatice intracellular pathogens
- 6 species
Pathogenesis and pathogenicity
- Penetrate nasal, oral or pharyngeal mucosa
- Phagocytosed and carried to regional lymph nodes
- Survive and multiply in cells of the reticulo-endothelial system
- Inhibit lysosome-phagosome fusion
- Lymph nodes enlarge (lymphatic and lymphoreticular hyperplasia) and inflammation is induced
- Surviving organisms spread to other organs (liver, spleen, placenta) and cause granulomatous reactions
- Eythritol is a growth stimulant and attracts the bacteria to the bovine placenta
- Infection of foetus and abortion
Clinical disease
Diagnosis
Control
- Serological testing of milk (Milk Ring Test) and beef cattle (Rose Bengal Plate Test)
- Serological tests detect anti-lipopolysaccharide antibodies