Difference between revisions of "Campylobacter species"
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| − | # | + | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> |
| + | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | ||
| + | * Curved, microaerophilic Gram-negative bacteria. | ||
| + | * Sensitive to drying. | ||
| + | |||
| + | * Linked to: | ||
| + | ** [[Intestines - Catarrhal Enteritis#Undifferentiated Neonatal Calf Diarrhoea|Undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves. | ||
| + | ** Food poisoning ([[Intestines - disease due to pathogens#Campylobacter jejuni|Campylobacter jejuni]]). | ||
| + | |||
| + | ===Overview=== | ||
| + | |||
| + | *Live on mucosa of intestinal and genital tract and can be commensals or pathogens | ||
| + | *Enteric species cause disease in humans | ||
| + | *Other species cause infertility and abortion in cattle and sheep | ||
| + | *Excreted in faeces of birds, (''C. jejuni'' and ''C. lari'') as well as pigs contaminating water and food supplies | ||
| + | *''C. fetus'' restricted to bovine prepucial mucosa | ||
| + | |||
| + | |||
| + | ===Characteristics=== | ||
| + | |||
| + | *Curved, Gram negative rods | ||
| + | *Polar flagellum aids motility | ||
| + | *Daughter cells remain joined giving gull-wing or spiral appearance | ||
| + | *Microaerophilic | ||
| + | *Sensitive to drying | ||
| + | *Thermophilic species - ''C. jejuni, C. coli'' | ||
| + | *Non-thermophilic species e.g. ''C. fetus'' | ||
| + | *Grow on enriched media e.g. Skirrow agar in 1-10% carbon dioxide and 5-10% oxygen tension | ||
| + | *Many grow on MacConkey | ||
| + | *Oxidase positive, non-fermentative | ||
| + | *''C. fetus'' subspecies ''venerealis'' and subspecies ''fetus'' have small, round, smooth, translucent colonies | ||
| + | *''C. jejuni'' has small, flat, grey colonies with watery appearance | ||
| + | |||
| + | |||
| + | ===Pathogenesis and pathogenicity=== | ||
| + | |||
| + | *''C. fetus'' subspecies ''fetus'' and subspecies ''venerealis'' possess a microcapsule (S layer) which resists phagocytosis and serum-mediated destruction and enhances survival in the genital tract | ||
| + | *''C. jejuni'' attaches and invades host enterocytes and produces enterotoxin-like substances | ||
| + | |||
| + | |||
| + | ===Clinical infections=== | ||
| + | |||
| + | |||
| + | |||
| + | ===Diagnosis=== | ||
| + | |||
| + | |||
| + | |||
| + | ===Control=== | ||
| + | |||
| + | |||
| + | |||
| + | ===Treatment=== | ||
Revision as of 07:27, 18 May 2008
- Curved, microaerophilic Gram-negative bacteria.
- Sensitive to drying.
- Linked to:
- Undifferentiated neonatal calf diarrhoea, a mixed viral enteritis in calves.
- Food poisoning (Campylobacter jejuni).
Overview
- Live on mucosa of intestinal and genital tract and can be commensals or pathogens
- Enteric species cause disease in humans
- Other species cause infertility and abortion in cattle and sheep
- Excreted in faeces of birds, (C. jejuni and C. lari) as well as pigs contaminating water and food supplies
- C. fetus restricted to bovine prepucial mucosa
Characteristics
- Curved, Gram negative rods
- Polar flagellum aids motility
- Daughter cells remain joined giving gull-wing or spiral appearance
- Microaerophilic
- Sensitive to drying
- Thermophilic species - C. jejuni, C. coli
- Non-thermophilic species e.g. C. fetus
- Grow on enriched media e.g. Skirrow agar in 1-10% carbon dioxide and 5-10% oxygen tension
- Many grow on MacConkey
- Oxidase positive, non-fermentative
- C. fetus subspecies venerealis and subspecies fetus have small, round, smooth, translucent colonies
- C. jejuni has small, flat, grey colonies with watery appearance
Pathogenesis and pathogenicity
- C. fetus subspecies fetus and subspecies venerealis possess a microcapsule (S layer) which resists phagocytosis and serum-mediated destruction and enhances survival in the genital tract
- C. jejuni attaches and invades host enterocytes and produces enterotoxin-like substances