Difference between revisions of "Francisella tularensis"
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| − | + | <big><center>[[Infectious agents and parasites|'''BACK TO INFECTIOUS AGENTS AND PARASITES''']]</center></big> | |
| + | <big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big> | ||
===Overview=== | ===Overview=== | ||
| − | *Causes tularaemia in | + | *Causes tularaemia in animals and humans |
*Wildlife reservoir of infection, including rabbits, rodents, galliform birds and deer | *Wildlife reservoir of infection, including rabbits, rodents, galliform birds and deer | ||
*Survives in the soil for up to 4 months | *Survives in the soil for up to 4 months | ||
*Type A strains associated with terrestrial animal reservoirs; type B strains with water-borne infections and aquatic animals | *Type A strains associated with terrestrial animal reservoirs; type B strains with water-borne infections and aquatic animals | ||
*Ticks and deerfly act as vectors | *Ticks and deerfly act as vectors | ||
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*High lipid content; virulent isolates produce capsules | *High lipid content; virulent isolates produce capsules | ||
*Highly virulent type A stains, ''F. tularensis'' subspecies ''tularensis'' in North America; less virulent type B strains, ''F. tularensis'' subspecies ''holarctica'' in Eurasia and North America | *Highly virulent type A stains, ''F. tularensis'' subspecies ''tularensis'' in North America; less virulent type B strains, ''F. tularensis'' subspecies ''holarctica'' in Eurasia and North America | ||
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===Clinical infections=== | ===Clinical infections=== | ||
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Revision as of 14:02, 26 May 2008
Overview
- Causes tularaemia in animals and humans
- Wildlife reservoir of infection, including rabbits, rodents, galliform birds and deer
- Survives in the soil for up to 4 months
- Type A strains associated with terrestrial animal reservoirs; type B strains with water-borne infections and aquatic animals
- Ticks and deerfly act as vectors
Characteristics
- Gram negative rod with coccobacillary appearance
- Non-moltile, obligate aerobe
- Oxidase negative, weakly catalase positive
- Fastidious, requiring cysteine for growth on blood agar
- No growth on MacConkey
- Facultative intracellular pathogen
Pathogenesis and pathogenicity
- High lipid content; virulent isolates produce capsules
- Highly virulent type A stains, F. tularensis subspecies tularensis in North America; less virulent type B strains, F. tularensis subspecies holarctica in Eurasia and North America