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* Pheromones
 
* Pheromones
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Facial and flank pheromones are used by cats to mark their core territory; an area in which cats do not expect to encounter hostility from conspecifics. Behavioural therapy involving controlled exposure is best performed in an environment where the cat already feels secure, such as within its core territory. It is possible that the use of synthetic analogue of F3 (Feliway) may be used to enhance this effect. However, the limit of this effect has been shown in a study
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Facial and flank pheromones are used by cats to mark their core territory; an area in which cats do not expect to encounter hostility from conspecifics. Behavioural therapy involving controlled exposure is best performed in an environment where the cat already feels secure, such as within its core territory. It is possible that the use of synthetic analogue of F3 (Feliway) may be used to enhance this effect. This can help to provide a setting within which behavioural therapy can take place, but studies have indicated that the "calming" effect of the synthetic pheromone does not necessarily increase tolerance of handling and other procedures<ref>Kronen, P.W.,, Ludders, J.W., Erb, H.N., Moon, P.F., Gleed, R.D., Koski, S. (2006) A synthetic fraction of feline facial pheromones calms but does not reduce struggling in cats before venous catheterization. ''Vet Anaesth Analg". 33(4):258-65</ref>.
    
If the cat has already shown different levels of fear according to the appearance of the people it has encountered, then a list should be made of the features of appearance the cat tolerates least. Typically, animals least like tall people wearing dark clothing, hats or hoods, because these make them seem more threatening. This enables therapy to start with people who dress and behave in the ways that the cat is most likely to accept. A good starting point is to start with female volunteers sitting down and wearing light coloured casual clothing. Cats that show signs of fear when they hear unfamiliar voices may be desensitised to these noises using recordings or radio programmes.
 
If the cat has already shown different levels of fear according to the appearance of the people it has encountered, then a list should be made of the features of appearance the cat tolerates least. Typically, animals least like tall people wearing dark clothing, hats or hoods, because these make them seem more threatening. This enables therapy to start with people who dress and behave in the ways that the cat is most likely to accept. A good starting point is to start with female volunteers sitting down and wearing light coloured casual clothing. Cats that show signs of fear when they hear unfamiliar voices may be desensitised to these noises using recordings or radio programmes.
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