Difference between revisions of "Angiotensin Converting Enzyme"

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<big><center>[[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology|'''BACK TO RAAS''']]</center></big>
==Overview==
 
  
Angiotensin converting enzyme is known as '''ACE'''. It is a membrane bound '''metalloproteinase''' and converts Angiotensin 1 to Angiotensin 2.
 
[[Image:angiotensin.png|right|thumb|250px|Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).]]
 
  
 
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* Membrane bound metalloproteinase
It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary circulation and this is therefore, the site of action of the ACE inhibitor drugs.
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* Converts Agiotensin 1 to Angiotensin 2
 
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* Very important in the RAAS
 
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* Predominantly expressed on epithelial cell membranes in the pulmonary ciculation
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* The site of action of the group of drugs - ACE inhibitors
[[Category:Kidney Hormonal Regulators]]
 
[[Category:To Do - AimeeHicks]]
 

Revision as of 18:09, 4 July 2008

BACK TO RAAS


  • Membrane bound metalloproteinase
  • Converts Agiotensin 1 to Angiotensin 2
  • Very important in the RAAS
  • Predominantly expressed on epithelial cell membranes in the pulmonary ciculation
  • The site of action of the group of drugs - ACE inhibitors