| − | There are no published studies evaluating niacin toxicity in cats. In dogs one study reported bloody diarrhoea in 2 dogs that were fed approximately x250 the adult requirement, and chronic exposure (11 days) resulted in death.<ref>Chen KK, ''et al. ''(1938) '''Toxicity of nicotinic acid. '''''Proc Soc Exp Biol Med ''1938; 38: 241-245. </ref> In humans, where it is used to help manage hypercholesterolemia, a high intake niacin (x25 the minimum requirement) can cause peripheral vasodilation (i.e., “flushing”).<ref name ="Xenoulis" /> This side effect of therapeutic niacin has not been evaluated in dogs. | + | There are no published studies evaluating niacin toxicity in cats. In dogs one study reported bloody diarrhoea in 2 dogs that were fed approximately x250 the adult requirement, and chronic exposure (11 days) resulted in death.<ref>Chen KK, ''et al. ''(1938) '''Toxicity of nicotinic acid. '''''Proc Soc Exp Biol Med ''1938; 38: 241-245. </ref> In humans, where it is used to help manage hypercholesterolemia, a high intake niacin (x25 the minimum requirement) can cause peripheral vasodilation (i.e. “flushing”).<ref name ="Xenoulis" /> This side effect of therapeutic niacin has not been evaluated in dogs. |