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| − | {{review}} | + | {{OpenPagesTop}} |
| − | | + | ==Introduction== |
| − | ==Description== | |
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| − | Intestinal adenocarcinomas are a reasonably common malignant neoplasm of dogs and cats arising from the epithelial lining of the gastrointesinal tract. As yet, no causative organism or http://en.wikivet.net/index.php?title=Intestinal_Adenocarcinoma&action=editchemical agent has been identified for intestinal adenocarcinomas, but experiments have suggested that nitrosamines may have a role. Intestinal adenocarcinomas can be nodular or annular in appearance. By the time of diagnosis, they have often metastasised via the lymphatic and vascular routes, most commonly to the mesenteric lymph nodes. Other sites of metastasis include the liver, kidneys, peritoneal cavity, omentum and lungs. Intestinal adenocarcinomas display aggressive local growth and invasion, and tumours frequently recur after resection. | + | Intestinal adenocarcinomas are a reasonably common malignant neoplasm of dogs and cats arising from the epithelial lining of the gastrointesinal tract. As yet, no causative organism or chemical agent has been identified for intestinal adenocarcinomas, but experiments have suggested that nitrosamines may have a role. Intestinal adenocarcinomas can be nodular or annular in appearance. By the time of diagnosis, they have often metastasised via the lymphatic and vascular routes, most commonly to the mesenteric lymph nodes. Other sites of metastasis include the liver, kidneys, peritoneal cavity, omentum and lungs. Intestinal adenocarcinomas display aggressive local growth and invasion, and tumours frequently recur after resection. |
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| | ==Signalment== | | ==Signalment== |
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| | Various paraneoplastic syndromes have been associated with intestinal adenocarcinoma, including cutaneous disease and hyperviscosity syndromes. | | Various paraneoplastic syndromes have been associated with intestinal adenocarcinoma, including cutaneous disease and hyperviscosity syndromes. |
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| − | Differential diagnoses for intestinal adenocarcinoma include: intestinal foreign body, [[Inflammatory Bowel Disease|inflammatory bowel disease]], alimentary lymphoma, gastrointestinal parasitism, leiomyoma or leiomyosarcoma and [[Pancreatitis - Dog and Cat|pancreatitis]]. | + | Differential diagnoses for intestinal adenocarcinoma include: intestinal foreign body, [[Inflammatory Bowel Disease|inflammatory bowel disease]], alimentary lymphoma, gastrointestinal parasitism, leiomyoma or leiomyosarcoma and [[Pancreatitis|pancreatitis]]. |
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| | ===Laboratory Tests=== | | ===Laboratory Tests=== |
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| | * [http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/23307.htm| The Merck Veterinary Manual - Gastrointestinal Neoplasia] | | * [http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/23307.htm| The Merck Veterinary Manual - Gastrointestinal Neoplasia] |
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| − | ==Literature Search== | + | {{Learning |
| − | [[File:CABI logo.jpg|left|90px]]
| + | |Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis00654.asp, Canine large intestinal neoplasia] |
| − | | + | |literature search = [http://www.cabdirect.org/search.html?q=title%3A%28intestine%29+AND+title%3A%28Adenocarcinoma%29 Intestinal Adenocarcinoma publications] |
| − | | + | }} |
| − | Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
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| − | [http://www.cabdirect.org/search.html?q=title%3A%28intestine%29+AND+title%3A%28Adenocarcinoma%29 Intestinal Adenocarcinoma publications] | |
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| | ==References== | | ==References== |
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| | * White, R. A. S. (2003) Tumours of the intestines, in '''BSAVA Manual of Canine and Feline Oncology, (Second Edition)''' ''British Small Animal Veterinary Association''. | | * White, R. A. S. (2003) Tumours of the intestines, in '''BSAVA Manual of Canine and Feline Oncology, (Second Edition)''' ''British Small Animal Veterinary Association''. |
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| | [[Category:Intestines_-_Proliferative_Pathology]] | | [[Category:Intestines_-_Proliferative_Pathology]] |
| − | [[Category:Intestinal Pathology - Dog]][[Category:Cat]] | + | [[Category:Intestinal Diseases - Dog]][[Category:Intestinal Diseases - Cat]] |
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| | [[Category:Expert_Review]] | | [[Category:Expert_Review]] |