Changes

====Cats:====  

====Cats:====  

Induced vitamin B₆ deficiency in kittens was reported to result in poor growth rate, microcytic hypochromic anaemia, and [[Urolithiasis#Calcium oxalate|calcium oxalate]] crystalluria<ref>Bai SC, et al. Vitamin B6 deficiency in kittens. J Nutr 1989;119: 1020-1027.</ref>. Increased dietary intake of [[Protein Overview - Nutrition|protein]] has also been show to increase Vitamin B₆ requirement in cats<ref>Bai SC, et al. The level of dietary protein affects the vitamin B-6 requirement of cats. J Nutr 1991 121;1054-1061.</ref>.

Induced vitamin B₆ deficiency in kittens was reported to result in poor growth rate, microcytic hypochromic anaemia, and [[Urolithiasis#Calcium oxalate|calcium oxalate crystalluria]]<ref>Bai SC, et al. Vitamin B6 deficiency in kittens. J Nutr 1989;119: 1020-1027.</ref>. Increased dietary intake of [[Protein Overview - Nutrition|protein]] has also been show to increase Vitamin B₆ requirement in cats<ref>Bai SC, et al. The level of dietary protein affects the vitamin B-6 requirement of cats. J Nutr 1991 121;1054-1061.</ref>.

Vitamin B₆ is '''light sensitive and prone to degradation with heat processing'''. Conditions associated with diuresis (e.g., chronic disease, such as renal disease or [[Diabetes Insipidus|diabetes]], or therapeutic intervention, such as intravenous fluids or increased water intake with management of [[Cystitis|lower urinary diseases]]) can result in increased loss of Vitamin B₆ and may increase daily requirements. Patients on chronic haemodialysis are at an increased risk for development of deficiency.  

Vitamin B₆ is '''light sensitive and prone to degradation with heat processing'''. Conditions associated with diuresis (e.g. chronic disease, such as [[:Category:Kidney - Pathology|renal disease]] or [[Diabetes Insipidus|diabetes]], or therapeutic intervention, such as [[Fluid therapy|intravenous fluids]] or increased water intake with management of [[Cystitis|lower urinary diseases]]) can result in increased loss of Vitamin B₆ and may increase daily requirements. Patients on chronic haemodialysis are at an increased risk for development of deficiency.

==Toxicity==

==Toxicity==

There are no published toxicity reports in cats, but chronic high intake (i.e., >100x the requirement) of Vitamin B₆ can result in ataxia and tonic convulsions in dogs within 1 week of daily administration<ref>Hoover DM, et al. Ultrastructural Lesions of Pyridoxine Toxicity in Beagle Dogs. Vet Pathol 1981;18: 769-777.</ref><ref>Montpetit VJ, et al. Alteration of neuronal cytoskeletal organization in dorsal root ganglia associated with pyridoxine neurotoxicity. Acta Neuropathol 1988;76:71-81.</ref>.

There are no published toxicity reports in cats, but chronic high intake (i.e. >100x the requirement) of Vitamin B₆ can result in ataxia and tonic convulsions in dogs within 1 week of daily administration<ref>Hoover DM, et al. Ultrastructural Lesions of Pyridoxine Toxicity in Beagle Dogs. Vet Pathol 1981;18: 769-777.</ref><ref>Montpetit VJ, et al. Alteration of neuronal cytoskeletal organization in dorsal root ganglia associated with pyridoxine neurotoxicity. Acta Neuropathol 1988;76:71-81.</ref>.

==Dietary Sources==

==Dietary Sources==

==References==

==References==

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[[Category:Vitamins]]

[[Category:Vitamins]]