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==Introduction==

==Description==

A highly malignant tumour of vascular endothelial origin. Commonly affect dogs and the most frequently affected areas are the spleen, pericardium, right atrium, liver and muscle.  The cat is affected less frequently and the most common sites are the liver, spleen and mesentry. Metastasis occurs via the haematogenous route or via rupture and transabdominal spread.  Metastatic sites include, lungs, liver, omentum, diaphragm and less commonly brain. Surgery is the treatment of choice but even with this survival time remains very short.

A highly malignant tumour of vascular endothelial origin. Commonly affect dogs and the most frequently affected areas are the spleen, pericardium, right atrium, liver and muscle.  The cat is affected less frequently and the most common sites are the liver, spleen and mesentry. Metastasis occurs via the haematogenous route or via rupture and transabdominal spread.  Metastatic sites include, lungs, liver, omentum and diaphragm. Surgery is the treatment of choice but even with this survival time remains very short.

==Signalment==

==Signalment==

==History and Clinical Signs==

==History and Clinical Signs==

Can vary depending on the anatomic site that the mass is affecting.

Can vary depending on the anatomic site that the mass is affecting.

Signs such as anorexia, lethargy, weakness, [[vomiting]] and [[:Category:Anaemia|anaemia]] are common.

Signs such as anorexia, lethargy, weakness, [[vomiting]] and [[Regenerative and Non-Regenerative Anaemias|anaemia]] are common.

Animals can also present collapsed following the rupture of the mass, leading to a haemoabdomen or occasionally can be found dead.  

Animals may have history of multiple episodes of collapse following repeated rupture of an abdominal mass, leading to non-fatal haemoabdomen. Occasionally can be found dead following catastrophic rupture and fatal haemoabdmen.  

In instances where the heart is involved animals may present in [[:Category:heart Failure|heart failure]]. If there is muscular involvement this often presents as a hard swollen mass.

In instances where the heart (right auricle) is involved, animals may die suddenly or present in [[:Category:heart Failure|heart failure]]. Rupture of the mass and haemorrhage into the pericardial sac leads to compression of the heart, which can no longer fill with blood during diastole ([[Cardiac Tamponade|cardiac tamponade]]).

If the nervous system is involved a range of neurological abnormalities will also be present.

If the nervous system is involved a range of neurological abnormalities will also be present.

==Laboratory Tests==

==Laboratory Tests==

====Haematology====

====Haematology====

[[Anaemia - Introduction|Anaemia]] will be evident which may be regenerative if due to blood loss, or microangiopathic due to the passage of [[erythrocytes|red blood cells]] through the microvascular network of the tumour.

Anaemia will be evident which may be [[Regenerative and Non-Regenerative Anaemias|regenerative]] if due to blood loss, or microangiopathic due to the passage of [[erythrocytes|red blood cells]] through the microvascular network of the tumour.

This results in the presence of schistocytes in dogs but not cats.

This results in the presence of schistocytes in dogs but not cats.

A [[Neutrophilia|neutrophilia]] and [[Platelet Abnormalities#Thrombocytopaenia|thrombocytopenia]] may also be present.

A [[Neutrophilia|neutrophilia]] and [[Platelet Abnormalities#Thrombocytopaenia|thrombocytopenia]] may also be present.

Poor due to high risk of metastasis in the early course of the disease.

Poor due to high risk of metastasis in the early course of the disease.

==Test yourself with the Liver Pathology Flashcards==

 

|Vetstream = [https://www.vetstream.com/canis/Content/Disease/dis01993.asp Haemangiosarcoma]

[[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]

|flashcards = [[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]]

 

|literature search = [http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Haemangiosarcoma&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&x=55&y=10&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Haemangiosarcoma]

==Literature Search==

 

 

[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=Haemangiosarcoma&occuring1=title&rowId=2&options2=AND&q2=&occuring2=freetext&rowId=3&options3=AND&q3=&occuring3=freetext&x=55&y=10&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Haemangiosarcoma]

==References==

==References==

[[Category:Liver,_Primary_Tumours]][[Category:Dog]][[Category:Cat]]

[[Category:Liver,_Primary_Tumours]][[Category:Cardiac Diseases - Dog]][[Category:Lymphoreticular and Haematopoietic Diseases - Dog]][[Category:Peritoneal Cavity Diseases - Dog]][[Category:Cardiac Diseases - Cat]][[Category:Lymphoreticular and Haematopoietic Diseases - Cat]][[Category:Peritoneal Cavity Diseases - Cat]]

[[Category:Peritoneal_Cavity_-_Neoplastic_Pathology]]

[[Category:Peritoneal_Cavity_-_Neoplastic_Pathology]]

[[Category:Neoplasia]][[Category:Splenic Neoplasia]]

[[Category:Neoplasia]][[Category:Splenic Neoplasia]]

[[Category:Expert_Review]]

[[Category:Expert_Review]]