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| | Also Known As: '''''Gall sickness''''' — '''''Gallsickness''''' — '''''Tick fever''''' (Australia) — '''''Tristeza''''' (Portugal) | | Also Known As: '''''Gall sickness''''' — '''''Gallsickness''''' — '''''Tick fever''''' (Australia) — '''''Tristeza''''' (Portugal) |
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| − | Caused by: '''''Anaplasma marginale — Anaplasma ovis — A. ovis — Ehrlichia bovis | + | Caused by: '''''[[Anaplasmas|Anaplasma marginale — A. ovis — A. mesaeterum]] — Ehrlichia bovis |
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| | ==Introduction== | | ==Introduction== |
| | [[File:Anaplasmosis.jpg|thumb|200px|right|''Rickettsia'' sp. inside tick haemolymph cells (sourced from Wikimedia Commons)]] | | [[File:Anaplasmosis.jpg|thumb|200px|right|''Rickettsia'' sp. inside tick haemolymph cells (sourced from Wikimedia Commons)]] |
| − | Anaplasmosis is a ruminant disease caused by the [[:Category:Rickettsiales|'''rickettsial''']] pathogens ''Anaplasma marginale'', ''A. ovis'', ''A. mesaeterum'' and ''Ehrlichia bovis''. | + | Anaplasmosis is a ruminant disease caused by the [[:Category:Rickettsiales|'''rickettsial''']] pathogens [[Anaplasmas|''Anaplasma marginale'', ''A. ovis'', ''A. mesaeterum'']] and ''Ehrlichia bovis''. |
| | These rickettsial parasites reside exclusively within the '''[[erythrocytes| red blood cells]]''' of their hosts. | | These rickettsial parasites reside exclusively within the '''[[erythrocytes| red blood cells]]''' of their hosts. |
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| | ==Clinical Signs== | | ==Clinical Signs== |
| | '''Cardiovascular''' | | '''Cardiovascular''' |
| − | :Profound anaemia resulting in tachycardia and dyspnoea. Congestion of mucous membranes. | + | :Profound anaemia resulting in tachycardia and dyspnoea. Congestion of mucous membranes which may be jaundiced. |
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| | '''Gastrointestinal''' | | '''Gastrointestinal''' |
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| | '''Urinary''' | | '''Urinary''' |
| − | :Red, brown or pink urine | + | :Haemoglobinuria does '''not''' occur |
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| | '''Neurological signs''' | | '''Neurological signs''' |
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| | '''Other''' | | '''Other''' |
| − | :Swelling of the head, face and ears, general paresis/paralysis, rough hair coat | + | :General paresis/paralysis, rough hair coat, weight loss |
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| − | Signs are often severely exacerbated by '''exercise'''. | + | Signs are often severely exacerbated by '''exercise''' with caution needed not to overly stress animals during clinical examination which can lead to collapse and death. |
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| | ==Diagnosis== | | ==Diagnosis== |
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| | Serous effusions may be present in any body cavity. The spleen may be engorged and the kidneys congested. | | Serous effusions may be present in any body cavity. The spleen may be engorged and the kidneys congested. |
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| − | Urine is dark yellow/brown due to the presence of [[Bilirubin | bilirubin]]. | + | Urine is dark yellow/brown due to the presence of [[Bilirubin | bilirubin]]. The absence of haemoglobinuria/haematuria is a useful sign to distinguish the condition from other differential diagnoses that present in a similar way. |
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| | ==Treatment== | | ==Treatment== |
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| | Supportive treatment such as '''blood transfusions''' and appetite stimulants in severe cases may be required. | | Supportive treatment such as '''blood transfusions''' and appetite stimulants in severe cases may be required. |
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| − | A long combined course of imidocarb and oxytetracycline can also be used to eliminate the carrier state. | + | A long combined course of imidocarb and oxytetracycline can also be used to try and eliminate the carrier state. However, a trial into using oxytetracycline for this purpose showed it to be ineffective for this purpose <ref>Coetzee ''et al'' (2005) '''Comparison of three oxytetracycline regimes for the treatment of persistent Anaplasma marginale infections in beef cattle. '''''Veterinary Parasitology'' 127:61-73.</ref>. |
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| | ==Control== | | ==Control== |
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| | [[Tick Control|Control of the tick vector]] is viable but expensive. | | [[Tick Control|Control of the tick vector]] is viable but expensive. |
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| | + | {{Learning |
| | + | |literature search = [http://www.cabdirect.org/search.html?q=title%3A+Anaplasmosis/ Anaplasmosis Publications] |
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| | + | |flashcards = [[Anaplasmosis Flashcards]] |
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| | ==References== | | ==References== |
| | <references/> | | <references/> |
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| − | Animal Health & Production Compendium, Anaplasmosis datasheet, accessed online 02/06/2011 @ http://www.ahpc.org/
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| − | {{review}} | + | {{CABI source |
| | + | |datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=94682&loadmodule=datasheet&page=2144&site=160 Anaplasmosis]] |
| | + | |date = June 2, 2011 |
| | + | }} |
| | + | <br><br><br> |
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| | + | {{Nick Lyons |
| | + | |date = October 16, 2011}} |
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| | [[Category:Lymphoreticular and Haematopoietic Diseases - Cattle]] | | [[Category:Lymphoreticular and Haematopoietic Diseases - Cattle]] |
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| − | [[Category:CABI Expert Review]] | + | [[Category:CABI Expert Review Completed]][[Category:CABI AHPC Pages]] |
| − | [[Category:Anaemia]] | + | [[Category:Anaemia|3]] |
| | + | [[Category:Nick Lyons reviewed]] |