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[[Image:Deep Lymphatic Drainage Diagram.jpg|right|thumb|200px|Deep Lymphatic drainage - Copyright B.Catchpole RVC]]

[[Image:Deep Lymphatic Drainage Diagram.jpg|right|thumb|200px|Deep Lymphatic drainage - Copyright B.Catchpole RVC]]

==Introduction==

==Introduction==

==Lymphatic Vessels and Lymph==

==Lymphatic Vessels and Lymph==

Due to their structure lymphatic capillaries are more permeable than vascular capillaries and this means that they can not only more effectively remove fluid from tissue but they can also take up large molecules as well as chylomicrons for the transport of fats. Chylomicrons enter the [[Lymph - Anatomy & Physiology|lymph]] to eventually join the blood via the thoracic duct; this enables the lipid soluble [[Small Intestine - Anatomy & Physiology#Triacylglycerol Digestion and Absorption |triacylglycerol (TAG)]] to be transported into the blood. The interstitial fluid or lymph within the lymphatic vessels passes through lymph nodes and is surveyed by immune cells before returning to the blood, ensuring that antigens/pathogens from tissues are removed.

Due to their structure lymphatic capillaries are more permeable than vascular capillaries which  means that not only can they remove fluid more effectively from tissues but they can also take up large molecules as well as chylomicrons. Chylomicrons transport fats and enter the [[Lymph - Anatomy & Physiology|lymph]] to eventually join the circulatory system via the thoracic duct; this enables the lipid soluble [[Small Intestine Overview - Anatomy & Physiology#Triacylglycerol Digestion and Absorption |triacylglycerols (TAGs)]] to be transported into the bloodstream. The interstitial fluid or lymph within the lymphatic vessels passes through lymph nodes where it is surveyed by [[Immunology|immune cells]] before returning to the circulation, ensuring that tissue pathogens are removed.

==Lymphoreticular system==

==[[:Category:Lymphoreticular System|Lymphoreticular system]]==

The lymphoreticular system produces [[Immunology|immune cells]] and removes senescent cells.

The lymphoreticular system produces [[Immunology|immune cells]] and removes senescent cells.

Primary (or central) lymphoid tissues can also be referred to as primary lymphoid organs. Maturation of [[Lymphocytes|lymphocytes]] and [[Leukopoiesis#Lymphopoiesis|lymphopoiesis]] occurs in the primary lymphoid tissues, with different tissues responsible for maturing different types of lymphocyte. The primary lymphoid tissues are:

Primary (or central) lymphoid tissues can also be referred to as primary lymphoid organs. Maturation of [[Lymphocytes - Introduction|lymphocytes]] and [[Leukopoiesis#Lymphopoiesis|lymphopoiesis]] occurs in the primary lymphoid tissues, with different tissues responsible for maturing different types of lymphocyte. The primary lymphoid tissues are:

*[[Bone Marrow - Anatomy & Physiology|Bone marrow]]

*[[Bone Marrow - Anatomy & Physiology|Bone marrow]]

*[[Bursa of Fabricius - Anatomy & Physiology|The Bursa of Fabricius]]

*[[Bursa of Fabricius - Anatomy & Physiology|The Bursa of Fabricius]]

*[[Thymus - Anatomy & Physiology|The Thymus]]

*[[Thymus - Anatomy & Physiology|The Thymus]]

*[[Haematopoiesis#Hepatic Phase|The Foetal Liver]]

*[[Haematopoiesis - Overview#Hepatic Phase|The Foetal Liver]]

Secondary (or peripheral) lymphoid tissues or secondary lymphoid organs provide a site for immune responses to occur and are populated by relatively mature [[Lymphocytes#T cells|T cells]] and [[Lymphocytes#B cells|B cells]], [[Macrophages|macrophages]] and dendritic cells; each tissue seems to be preferentially populated by lymphocyte types that specialise in the antigens that are most likley to be presented at that site. The secondary lymphoid tissues are:

Secondary (or peripheral) lymphoid tissues or secondary lymphoid organs provide a site for immune responses to occur and are populated by relatively mature [[Lymphocytes#T cells|T cells]] and [[Lymphocytes#B cells|B cells]], [[Macrophages|macrophages]] and dendritic cells; each tissue seems to be preferentially populated by lymphocyte types that specialise in the antigens that are most likely to be presented at that site. The secondary lymphoid tissues are:

*[[Lymph Nodes - Anatomy & Physiology|The Lymph nodes]]

*[[Lymph Nodes - Anatomy & Physiology|The Lymph nodes]]

*[[Spleen - Anatomy & Physiology|The Spleen]]

*[[Spleen - Anatomy & Physiology|The Spleen]]

*[[Regional Lymphoid Tissue - Anatomy & Physiology|Regional lymphoid tissue]]

*[[Regional Lymphoid Tissue - Anatomy & Physiology|Regional lymphoid tissue]]

==Test yourself on the lymphoreticular flash cards==

==Functions==

[[Lymphoreticular System Flashcards - Wikiblood|Lymphoreticular Flashcards]]

#'''Immune defence''': This is a broad topic area.</p><p>Immune functions are covered broadly under the [[:Category:Primary Lymphoid Tissue|primary]] and [[:Category:Secondary Lymphoid Tissue|secondary]] lymphoid tissues of the [[Lymphoreticular System - Anatomy & Physiology|lymphoreticular system]] with further information under the [[Immunology|immunology]] section.

 

|flashcards = [[:Category:Lymphoreticular System Anatomy & Physiology Flashcards|Lymphoreticular Flashcards]]

==References==

==References==

*<div id="Nance">{{citation|initiallast = Nance|initialfirst = D.M|finallast = Sanders|finalfirst = V.M|year = 2007|jtitle = Autonomic innervation and regulation of the immune system (1987-2007)|jor = Brain, Behavior, and Immunity|vol = 21(6)|range = 736-745}}</div>

*<div id="Nance">{{citation|initiallast = Nance|initialfirst = D.M|finallast = Sanders|finalfirst = V.M|year = 2007|jtitle = Autonomic innervation and regulation of the immune system (1987-2007)|jor = Brain, Behavior, and Immunity|vol = 21(6)|range = 736-745}}</div>

==Creator==

[[Asher Allison]]

 

==Webinars==

 

[[Category:Lymphoreticular System]]