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| − | ==Description== | + | ==Introduction== |
| − | Modified transudates are a type of effusion whose cell count and protein content are intermediate between a [[Transudate|transudate]] and an [[Exudate|exudate]]. In some cases, modified transudates may represent a transitional stage before the development of an exudate (as with uroabdomen, which begins as a modified transudate but develops into a chemical exudative peritonitis over time). Modified transudates arise as a result of disruptions to the endothelium or imbalances in the [[Control of Blood Pressure & Blood Flow - Anatomy & Physiology#Capillary Fluid Shift Mechanism |'''Starling forces''']]. Common causes include: | + | Modified transudates are a type of effusion whose cell count and protein content are intermediate between a [[Transudate|transudate]] and an [[Exudate|exudate]]. In some cases, modified transudates may represent a transitional stage before the development of an exudate (as with uroabdomen, which begins as a modified transudate but develops into a chemical exudative peritonitis over time). Modified transudates arise as a result of disruptions to the endothelium or imbalances in the [[Blood Pressure Physiology#Capillary Fluid Shift Mechanism |'''Starling forces''']]. Common causes include: |
| | *'''Increased vascular hydrostatic pressure''' resulting from inappropriate activation of the renin-angiotensin-aldosterone system (RAAS) in '''portal hypertension''' or '''congestive heart failure'''. | | *'''Increased vascular hydrostatic pressure''' resulting from inappropriate activation of the renin-angiotensin-aldosterone system (RAAS) in '''portal hypertension''' or '''congestive heart failure'''. |
| | *'''Vasculitis''', caused by '''[[Feline Infectious Peritonitis|feline infectious peritonitis virus]]''' (FIPV) or '''neoplasia'''. ([[Feline Infectious Peritonitis|Further discussion of the effusion encountered with FIP.]]) | | *'''Vasculitis''', caused by '''[[Feline Infectious Peritonitis|feline infectious peritonitis virus]]''' (FIPV) or '''neoplasia'''. ([[Feline Infectious Peritonitis|Further discussion of the effusion encountered with FIP.]]) |
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| | | Nucleated cells | | | Nucleated cells |
| − | | 0.3 - 5.5 x10e9/L (up to 7 x 10e9/L), of which the majority are [[Mesothelial cells|mesothelial cells]], [[Macrophages|macrophages]], non-degenerate neutrophils and small [[Lymphocytes|lymphocytes]] | + | | 0.3 - 5.5 x10e9/L (up to 7 x 10e9/L), of which the majority are [[Mesothelial cells|mesothelial cells]], [[Macrophages|macrophages]], non-degenerate neutrophils and small [[Lymphocytes - Introduction|lymphocytes]] |
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| | The presence of neoplastic cells in an effusion should prompt further investigation through diagnostic imaging or exploratory surgery. | | The presence of neoplastic cells in an effusion should prompt further investigation through diagnostic imaging or exploratory surgery. |
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| | + | {{Learning |
| | + | |literature search = [http://www.cabdirect.org/search.html?q=ab%3A%28%22Modified+Transudate%22%29 Modified transudate publications] |
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| | + | {{review}} |
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| | + | ==Webinars== |
| | + | <rss max="10" highlight="none">https://www.thewebinarvet.com/clinical-pathology/webinars/feed</rss> |
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| | [[Category:Effusions]] | | [[Category:Effusions]] |
| − | [[Category:To_Do_-_James]]
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| − | [[Category:Dog]][[Category:Cat]][[Category:Horse]][[Category:Cattle]]
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| | [[Category:Expert_Review]] | | [[Category:Expert_Review]] |