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*The mucosa of the large intestine is smooth; there are '''no villi or microvilli'''.
 
*The mucosa of the large intestine is smooth; there are '''no villi or microvilli'''.
 
*Mucosal glands are much longer and straighter.
 
*Mucosal glands are much longer and straighter.
*The number of goblet cells in the mucosa is increased compared to the small intestine.
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*The number of goblet cells in the mucosa is increased compared to the [[Small Intestine - Anatomy & Physiology|small intestine]].
 
**Mucus is very important for lubrication of the ingesta as it passes through the intestine, particularly as more water is absorbed from the lumen making chyme drier.
 
**Mucus is very important for lubrication of the ingesta as it passes through the intestine, particularly as more water is absorbed from the lumen making chyme drier.
 
*There are numerous scattered lymph nodules.
 
*There are numerous scattered lymph nodules.
**The number of lymph nodules increases compared to the small intestine.
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**The number of lymph nodules increases compared to the [[Small Intestine - Anatomy & Physiology|small intestine]].
 
*The submucosa is much reduced in thickness.
 
*The submucosa is much reduced in thickness.
 
*'''Taenia''' may be present.
 
*'''Taenia''' may be present.
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