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**Morbidity up tp 50%
 
**Morbidity up tp 50%
 
**Affects mostly unthrifty lmbs
 
**Affects mostly unthrifty lmbs
**Fibrosis and [[Musculoskeletal terminology|osteophyte]] formation in later stages -> persistent lameness
+
**Fibrosis and [[Musculoskeletal Terminology - Pathology|osteophyte]] formation in later stages -> persistent lameness
 
*[[Corynebacterium species|'''''Corynebacterium pyogenes''''']]
 
*[[Corynebacterium species|'''''Corynebacterium pyogenes''''']]
 
**May cause post-dipping joint infections
 
**May cause post-dipping joint infections
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**Chronic stage
 
**Chronic stage
 
***More commonly encountered
 
***More commonly encountered
***Erosion of articular surface of joints with formation of [[Musculoskeletal terminology|pannus +/- joint ankylosis]]
+
***Erosion of articular surface of joints with formation of [[Musculoskeletal Terminology - Pathology|pannus +/- joint ankylosis]]
 
***Vaccination prevents septicaemic and urticarial forms but has no effect on joints
 
***Vaccination prevents septicaemic and urticarial forms but has no effect on joints
 
****Probably due to dead bacteria still stimulating host immune system
 
****Probably due to dead bacteria still stimulating host immune system
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***Mineralisation
 
***Mineralisation
 
***Mononuclear cell infiltration
 
***Mononuclear cell infiltration
***[[Musculoskeletal terminology|Pannus]] formation
+
***[[Musculoskeletal Terminology - Pathology|Pannus]] formation
 
***[[Joints - normal#Articular cartilage|Articular cartilage]] destruction  
 
***[[Joints - normal#Articular cartilage|Articular cartilage]] destruction  
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**Marked villus hypertrophy of synovial membrane
 
**Marked villus hypertrophy of synovial membrane
 
**Cartilage erosion
 
**Cartilage erosion
**[[Musculoskeletal terminology|Pannus and periarticular osteophyte]] formation
+
**[[Musculoskeletal Terminology - Pathology|Pannus and periarticular osteophyte]] formation
 
**In severe cases ankylosis
 
**In severe cases ankylosis
 
*Histologically:
 
*Histologically:

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