Difference between revisions of "Type II Hypersensitivity"
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− | + | <big><center>[[Immunology - WikiBlood|'''BACK TO IMMUNOLOGY''']]</center></big> | |
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[[Image:Type II Hypersensitivity.jpg|right|thumb|150px|Type II Hypersensitivity-Brian Catchpole RVC 2008]] | [[Image:Type II Hypersensitivity.jpg|right|thumb|150px|Type II Hypersensitivity-Brian Catchpole RVC 2008]] | ||
− | Production of | + | Production of IgM or IgG to cell surface antigens or extracellular matrix proteins. |
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''' "Neutralisation" blockade of receptors:''' | ''' "Neutralisation" blockade of receptors:''' | ||
− | * | + | * Myasthenia gravis |
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− | ''' Immunological attack on target cells, destroying them by | + | ''' Immunological attack on target cells, destroying them by:''' |
− | + | 1. Antibody dependent cell cytotoxicity (ADCC) | |
− | * | + | * Pemphigus vulgaris |
− | * | + | * Bullous pemphigoid |
− | 2. | + | 2. Complement mediated lysis |
− | * Self | + | * Self RBC antigen: |
− | ** | + | ** Immune mediated haemolytic anaemia |
− | * Foreign | + | * Foreign RBC: |
** Blood transfusion reaction | ** Blood transfusion reaction | ||
− | ** | + | ** Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens) |
* RBC parasite: | * RBC parasite: | ||
** Feline infectious anaemia (''Mycoplasma haemofelis'') | ** Feline infectious anaemia (''Mycoplasma haemofelis'') | ||
3. Phagocytosis | 3. Phagocytosis | ||
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Revision as of 13:55, 26 August 2008
Production of IgM or IgG to cell surface antigens or extracellular matrix proteins.
"Neutralisation" blockade of receptors:
- Myasthenia gravis
Immunological attack on target cells, destroying them by:
1. Antibody dependent cell cytotoxicity (ADCC)
- Pemphigus vulgaris
- Bullous pemphigoid
2. Complement mediated lysis
- Self RBC antigen:
- Immune mediated haemolytic anaemia
- Foreign RBC:
- Blood transfusion reaction
- Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
- RBC parasite:
- Feline infectious anaemia (Mycoplasma haemofelis)
3. Phagocytosis