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Immunodeficiencies - WikiBlood (view source)
Revision as of 11:03, 9 September 2008
, 11:03, 9 September 2008→Deficiencies of Innate Immunity
===Deficiencies of Innate Immunity===
===Deficiencies of Innate Immunity===
[[Image:Grey Collie Syndrome.jpg|thumb|right|150px|Appearance of a puppy with Grey Collie syndrome - Copyright Michelle Tennis & Peggy Melton]]
====Canine Cyclic Haematopoiesis====
====Canine Cyclic Haematopoiesis====
*Also called '''Grey Collie Syndrome'''
*Also called '''Grey Collie Syndrome'''
*Diluted grey coat colour, stunted growth, poor wound healing
*Diluted grey coat colour, stunted growth, poor wound healing
*Neutropenia every 2 weeks which lasts 3-4 days due to cyclic production of cells from [[Bone Marrow - Anatomy & Physiology|bone marrow]]
*Neutropenia every 2 weeks which lasts 3-4 days due to cyclic production of cells from [[Bone Marrow - Anatomy & Physiology|bone marrow]]
*Recurrent infections, e.g. pyrexia, [[Intestine Diarrhoea - Pathology|diarrhoea]], gingivitis and arthritis
*Animals are prone to recurrent infections, mainly from the respiratory and gastrointestinal tract
**E.g. pyrexia, [[Intestine Diarrhoea - Pathology|diarrhoea]], gingivitis and arthritis
*Puppies can be distinguised from other litter mates by the diluted grey collouring
*Affected puppies show symptoms such as fever, joint pain and eye, skin and respiratory infections from 8 weeks of age
*Affected animals rarely live beyond 2-3 years with most puppies dying withing a few weeks of birth
====Canine Leukocyte Adhesion Deficiency (CLAD)====
====Canine Leukocyte Adhesion Deficiency (CLAD)====