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Sertoli Cell Tumour (view source)
Revision as of 18:41, 20 September 2008
, 18:41, 20 September 2008New page: {{toplink |backcolour = FAFAD2 |linkpage =Endocrine System - Pathology |linktext =Endocrine System |maplink = Endocrine System (Content Map) - Pathology |pagetype =Pathology |sublink1=Sex ...
{{toplink
|backcolour = FAFAD2
|linkpage =Endocrine System - Pathology
|linktext =Endocrine System
|maplink = Endocrine System (Content Map) - Pathology
|pagetype =Pathology
|sublink1=Sex hormones - Pathology
|subtext1=SEX HORMONES
}}
<br>
Sertoli cells are those which act as ''nurse cells'' to the developing spermatozoa. The sertoli cells engulf the spermatozoa, are structurally important in the seminiferous tubules and form the blood-testis barrier.
Tumours are usually slow growing although 10-20% show malignant characteristics.
Neoplasia is predisposed by inguinal or abdominal testes.
Sertoli cell tumours usually present as a feminising syndrome in the elderly dog. Owners may also notice:
*Asymmetric testes.
*Swelling in one testis.
*Infertility/subfertility in a breeding dog.
Treatment involves castration. Metastasis is rare but can occur, in which case chemotherapy is a possible treatment option.
|backcolour = FAFAD2
|linkpage =Endocrine System - Pathology
|linktext =Endocrine System
|maplink = Endocrine System (Content Map) - Pathology
|pagetype =Pathology
|sublink1=Sex hormones - Pathology
|subtext1=SEX HORMONES
}}
<br>
Sertoli cells are those which act as ''nurse cells'' to the developing spermatozoa. The sertoli cells engulf the spermatozoa, are structurally important in the seminiferous tubules and form the blood-testis barrier.
Tumours are usually slow growing although 10-20% show malignant characteristics.
Neoplasia is predisposed by inguinal or abdominal testes.
Sertoli cell tumours usually present as a feminising syndrome in the elderly dog. Owners may also notice:
*Asymmetric testes.
*Swelling in one testis.
*Infertility/subfertility in a breeding dog.
Treatment involves castration. Metastasis is rare but can occur, in which case chemotherapy is a possible treatment option.