Changes

===Osmotic Diuretics===

===Osmotic Diuretics===

These are compounds which are filtered but not reabsorbed.  They increase the osmolarity of the fluid and therefore hold more water in the tubules.  However they require intravenous administration.  They mainly act on sites freely permeable to water - [[Proximal Tubule - Anatomy & Physiology |the proximal tubule]], [[Reabsorption and Secretion Along the Loop of Henle - Anatomy & Physiology#Thin descending limb|the descending limb of the loop of henle]] and [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology|the collecting ducts]].  However they also reduce the sodium uptake as relatively sodium concentration drops in the lumen when they are present.

These are compounds which are filtered but not reabsorbed.  They increase the osmolarity of the fluid and therefore hold more water in the tubules.  However they require intravenous administration.  They mainly act on sites freely permeable to water - [[Reabsorption and Secretion Along the Proximal Tubule - Anatomy & Physiology|the proximal tubule]], [[Reabsorption and Secretion Along the Loop of Henle - Anatomy & Physiology#Thin descending limb|the descending limb of the loop of henle]] and [[Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology|the collecting ducts]].  However they also reduce the sodium uptake as relatively sodium concentration drops in the lumen when they are present.