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Changes
→Levamisole
* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
* It is a cholinergic agonist at neural and nuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
* It is rapidly absorbed and excreted and it's potency is related to it's peak plasma concentration. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.
==Morantel==
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
* It has limited activity against larval forms and so has little uses.
* Morantel is used in some rumenal boluses.
* Pyrantel, a similar product, is used for against equine [[cestodes]].