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'''Pathogenesis'''
 
'''Pathogenesis'''
*Causes[[Muscles Inflammatory - Pathology#Arthropods|myositis]]
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*Causes[[Muscles Inflammatory - Pathology#Arthropods| myositis]]
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*Production losses
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**Condemnation and down-grading of hides
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**Reduced milk yield and reduced weight gain
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**Injury from stock panic
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**Trimmed meat losses from ''H. lineatum''
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***'Butcher's Jelly' around warbles which is green due to mass [[Eosinophils - WikiBlood|eosinophil]] attraction
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*Paraplegia resulting from:
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**Toxin release
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**Pressure on the spinal cord (''H. bovis'')
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**Bloat from pressue on the oesophageal wall (''H. lineatum'')
    
'''Control'''
 
'''Control'''
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*Total eradication should be aimed for
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*Old methods include popping out warbles
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**But could lead to anaphylactic shock
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*[[Ectoparasiticides]]
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**Systemic organophosphorus [[Ectoparasiticides|insecticides]] in pour-on formula
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**Avermectins and milbemycins in pour-on and injectible formulations
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*Timing is crucial for treatment
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**Larvae residing in winter resting sites, if killed, can lead to bloat and paraplegia
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**It is safe to treat in the '''autumn''' before larvae reach their winter resting sites and in the '''spring''' when the warbles have migrated to the midline of the back
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**Ivermectin can be given at any time without risking host infection as larval antigen is released much slower
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'''Legislation in the UK'''
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*'Warble Fly Order 1978' requires all clinically affected animals to be treated
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*Notifiable disease
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*'Warble Fly Infected Area Order 1983'
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*For more information on the warble fly orders, see[http://www.defra.gov.uk/animalh/diseases/notifiable/brucellosis/surveillance.htm|here]
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===''Oestrus ovis''===
 
===''Oestrus ovis''===
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