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| '''Life Cycle''' | | '''Life Cycle''' |
| + | *Incubation phase lasts 1 week |
| | | |
− | '''Pathogenesis'''
| + | *Lymphoblast proliferation |
| + | **Local [[Lymph Nodes - Anatomy & Physiology|lymph node]] first infected then spreads through body |
| + | **Occurs in week two |
| + | |
| + | *Lymphoid depletion |
| + | **[[Lymphocytes - WikiBlood|Lymphocytes]] killed |
| + | **Decreases lymphopoiesis |
| + | **Occurs in week 3 |
| + | |
| + | *Total incubation period takes about 18 days |
| | | |
| '''Diagnosis''' | | '''Diagnosis''' |
| + | *Clinical signs |
| + | **Pyrexia |
| + | **Enlarged local [[Lymph Nodes - Anatomy & Physiology|lymph node]] |
| + | ***Usually parotid [[Lymph Nodes - Anatomy & Physiology|lymph node]] as [[Suborder: Metastigmata, ticks#Ticks of Veterinary Importance|''Rhipicephalus appendiculatus'']] feeds in the ear |
| + | **Loss of condition |
| + | |
| + | *Examine Giemsa stained smears of: |
| + | **Local lymph node aspirated for schizonts |
| + | **Blood smears for pioplasms in red blood cells |
| + | |
| + | *Post-mortem |
| + | **Pulmonary oedema |
| + | **Gut mucosal haemorrhages |
| + | **[[Lymph Nodes - Anatomy & Physiology|Lymph node]] and [[Spleen - Anatomy & Physiology|spleen]] cellular atrophy |
| | | |
| '''Control''' | | '''Control''' |