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→Side Effects and Contraindications
In addition to the CNS, phenothiazines also act on:
In addition to the CNS, phenothiazines also act on:
* The '''cardiovascular system'''.
* The '''cardiovascular system''', where they bind to alpha-1 adrenoreceptors leading to vasodilation, hypotension and hypothermia.
* The '''gastrointestinal tract'''.
* The '''gastrointestinal tract''', where they have an antispasmodic effect.
* Other '''receptors'''.
* Other '''receptors'''. Blockade of muscarinic receptors, histamine receptors and 5-HT occurs.