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| − | *Not significant cause of infection in domestic animals
| + | * Causes [[Intestines - disease due to pathogens#Dysentery in Humans and Primates|dysentery in humans and primates]]. |
| − | *Causes dysentery in humans and primates | |
| − | *Enteroinvasive, invading the intestinal mucosa and causing necrosis
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| − | *Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
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| − | *A large plasmid permits survival in cells and is responsible for invasivenss
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| − | *Closely related to [[Escherichia coli|''E. coli'']] - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli''
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| − | * Cause of dysentery in humans and primates.
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| − | ===Dysentery in Humans and Primates===
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| − | * [[Shigella|''Shigella'']] is are enteroinvasive,
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| − | ** Penetrate the intestinal mucosa.
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| − | ** Cause necrosis in patches of mucosa.
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| − | * [[Shigella|''Shigella'']] do not invade beyond the lamina propria to the bloodstream.
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| − | * Invasive potential is carried by a large plasmid.
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| − | ** Relates to the ability to survive inside the host cells.
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| − | * Some strains produce Shiga toxin.
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| − | ** Related to vero cytotoxin of some pathogenic strains of [[Escherichia coli|''E.coli'']].
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| − | [[Category:Enterobacteriaceae]]
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| − | [[Category:Enteritis,_Bacterial]]
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| − | [[Category:To_Do_-_Bacteria]]
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