− | Lymphocytic cholangitis is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly lymphocytes and plasma cells. Bile duct hypertrophy and fibrosis are present, however, lymphocytic cholangitis does not progress to biliary cirrhosis. An immune-mediated aetiology has been postulated, however, this has not been substantiated to date. It is rarely associated with pancreatitis. | + | '''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly lymphocytes and plasma cells. Bile duct hypertrophy and fibrosis are present, however, lymphocytic cholangitis does not progress to biliary cirrhosis. An immune-mediated aetiology has been postulated, however, this has not been substantiated to date. It is rarely associated with pancreatitis. |