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| | ==EMBRYOLOGICAL DEVELOPMENT OF THE GENITAL TRACT== | | ==EMBRYOLOGICAL DEVELOPMENT OF THE GENITAL TRACT== |
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| − | ===Early embryo==== | + | ===Early embryo=== |
| | Small indifferent gonads. The primitive structures which will become gonads and genital tract are identical at this stage. | | Small indifferent gonads. The primitive structures which will become gonads and genital tract are identical at this stage. |
| | Paired mesonephric ducts (Wolffian) or paramesonephric (Mullerian) ducts fuse caudally with urogenital sinus. | | Paired mesonephric ducts (Wolffian) or paramesonephric (Mullerian) ducts fuse caudally with urogenital sinus. |
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| | ==ANOMALIES OF DEVELOPMENT== | | ==ANOMALIES OF DEVELOPMENT== |
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| − | ===INTERSEX=== | + | ===Intersex=== |
| | This relates to developmental abnormalities resulting in discordance between genetic, gonadal or phenotypic sex and includes true hermaphrodites, pseudohermaphrodites and other forms of sex reversal. | | This relates to developmental abnormalities resulting in discordance between genetic, gonadal or phenotypic sex and includes true hermaphrodites, pseudohermaphrodites and other forms of sex reversal. |
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| | #Testicular feminisation: XY genotype with testosterone producing but sterile gonads internally and female external genitalia. The vagina is blind-ending with absence of internal genital tract. These male pseudohermaphrodites exhibit male behaviour and have significant testosterone levels. | | #Testicular feminisation: XY genotype with testosterone producing but sterile gonads internally and female external genitalia. The vagina is blind-ending with absence of internal genital tract. These male pseudohermaphrodites exhibit male behaviour and have significant testosterone levels. |
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| − | *'''FREEMARTIN SYNDROME (i.e. Chimeras)'''
| + | ===Freemartin Synodrome(i.e. Chimeras)=== |
| | A freemartin is a masculinised female born co-twin with a normal male. 11/12 female calves born co-twin to a male will be freemartins. The condition is mainly recognised in cattle, but occurs in sheep, goats and pigs. | | A freemartin is a masculinised female born co-twin with a normal male. 11/12 female calves born co-twin to a male will be freemartins. The condition is mainly recognised in cattle, but occurs in sheep, goats and pigs. |
| | <Br>During foetal development placental anastomosis allows blood to be shared by the twins (anastamosis occurs in 90% of bovine twins, <2% in other species).Each twin acquires genetically distinct population of blood cells from the other twin - CHIMERISM. | | <Br>During foetal development placental anastomosis allows blood to be shared by the twins (anastamosis occurs in 90% of bovine twins, <2% in other species).Each twin acquires genetically distinct population of blood cells from the other twin - CHIMERISM. |