Changes

**The toxin kills phagocytes, increases capillary permeability and interferes with clotting cascade

**The toxin kills phagocytes, increases capillary permeability and interferes with clotting cascade

**Capillary thrombosis; leakage of fluid through damaged capillary endothelium

**Capillary thrombosis; leakage of fluid through damaged capillary endothelium

**Systemic shock from circulatory collapse, [[General Pathology - Haemostasis#Haemorrhagic Disease Due To Vascular Fragility|haemorrhagic disease]] and oedema lead to death of the animal

**Systemic shock from circulatory collapse, [[Haemostasis - Pathology#Haemorrhagic Disease Due To Vascular Fragility|haemorrhagic disease]] and oedema lead to death of the animal

**Severe systemic disease that can result in [[Intestines Fibrinous/Haemorrhagic Enteritis - Pathology#Bacterial septicaemia and enteritis|enteritis]]

**Severe systemic disease that can result in [[Intestines Fibrinous/Haemorrhagic Enteritis - Pathology#Bacterial septicaemia and enteritis|enteritis]]

**Causes tissues to darken and swell due to oedema and necrosis

**Causes tissues to darken and swell due to oedema and necrosis