Changes

*Animals are prone to recurrent infections, mainly from the respiratory and gastrointestinal tract  

*Animals are prone to recurrent infections, mainly from the respiratory and gastrointestinal tract  

**E.g. pyrexia, [[Intestine Diarrhoea - Pathology|diarrhoea]], gingivitis and arthritis

**E.g. pyrexia, [[Intestine Diarrhoea - Pathology|diarrhoea]], gingivitis and arthritis

*Puppies can be distinguised from other litter mates by the diluted grey collouring

*Puppies can be distinguished from other litter mates by the diluted grey colouring

*Affected puppies show symptoms such as fever, joint pain and eye, skin and respiratory infections from 8 weeks of age

*Affected puppies show symptoms such as fever, joint pain and eye, skin and respiratory infections from 8 weeks of age

*Affected animals rarely live beyond 2-3 years with most puppies dying withing a few weeks of birth

*Affected animals rarely live beyond 2-3 years with most puppies dying within a few weeks of birth

====Canine Leukocyte Adhesion Deficiency (CLAD)====

====Canine Leukocyte Adhesion Deficiency (CLAD)====