Changes

Jump to navigation Jump to search
38 bytes added ,  11:17, 1 September 2009
Line 45: Line 45:  
===Buprenorphine===
 
===Buprenorphine===
   −
Buprenorphine is a Schedule 3 controlled drug used for the relief of moderate pain. It is licensed for veterinary used and may be given i/v, i/m, s/c or p/o. Its actions last 6-8 hours.
+
Buprenorphine is a Schedule 3 controlled drug used for the relief of moderate pain. It is licensed for veterinary used and may be given i/v, i/m, s/c or p/o. There is an onset time of 45 mins and its actions last 6-8 hours.
    
Buprenorphine is a partial OP3 agonist. This gives it a bell-shaped dose response curve, with large experimental doses actually causing opioid receptor antagonism. Buprenophine may therefore cause partial reversal of administration of full OP3 agonists such as [[#Morphine|morphine]], [[#Methadone|methadone]], [[#Pethidine|pethidine]] or [[#Fentanyl|fentanyl]].
 
Buprenorphine is a partial OP3 agonist. This gives it a bell-shaped dose response curve, with large experimental doses actually causing opioid receptor antagonism. Buprenophine may therefore cause partial reversal of administration of full OP3 agonists such as [[#Morphine|morphine]], [[#Methadone|methadone]], [[#Pethidine|pethidine]] or [[#Fentanyl|fentanyl]].
172

edits

Navigation menu