Difference between revisions of "Morantel"

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m (Levamisole and Morantel moved to Morantel: They belong to different drug classes.)
 
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These belong to the tetrahydropyrimidines class of drugs and a known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
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It belongs to the tetrahydropyrimidines class of drugs, which are known by farmers as yellow drenches. The product code in the UK is '''2-LM'''.
  
 
==Levamisole==
 
* This is one of the most widely used anthelmintics and can be given orally, by injection or as a pour on.
 
* It is active against adult '''[[Nematodes]]''', but has limited action against the larval stages, especially the hypobiotic phase.
 
* It is a cholinergic agonist at neural and nuromuscular junctions causing a '''spastic paralysis''' of the nematode. The nematodes succumb rapidly to it.
 
* It is rapidly absorbed and excreted and it's potency is related to it's peak plasma concentration. Therefore pour-on products need a higher dose, as they are absorbed more slowly, to reach the same plasma concentrations.
 
 
 
==Morantel==
 
 
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 
* This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
 
* It has limited activity against larval forms and so has little uses.
 
* It has limited activity against larval forms and so has little uses.
 
* Morantel is used in some rumenal boluses.
 
* Morantel is used in some rumenal boluses.
* Pyrantel, a similar product, is used for against equine [[cestodes]].
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* Pyrantel, a similar product, is used against equine [[cestodes]].

Latest revision as of 21:35, 29 September 2009


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It belongs to the tetrahydropyrimidines class of drugs, which are known by farmers as yellow drenches. The product code in the UK is 2-LM.

  • This works in a similar fashion to levamisole but isn't absorbed by the alimentary tract.
  • It has limited activity against larval forms and so has little uses.
  • Morantel is used in some rumenal boluses.
  • Pyrantel, a similar product, is used against equine cestodes.